CDKN1C

Aliases:
This biomarker is also known as:
  • WBS
  • p57Kip2
  • p57
  • cyclin-dependent kinase inhibitor p57
  • Beckwith-Wiedemann syndrome
  • cyclin-dependent kinase inhibitor 1C
  • CDKN1C
  • BWS
  • KIP2
  • P57
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • IMAGE
  • Cyclin-dependent kinase inhibitor p57
  • BWCR

Description…

From NCBI Gene: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: CDKN1C

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0