CD74

Aliases:
This biomarker is also known as:
  • HLADG
  • P33
  • Ia Antigen-Associated Invariant Chain
  • Ia-GAMMA
  • DHLAG
  • CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated)
  • CD74
  • MHC HLA-DR Gamma Chain
  • HLA-DR Antigens-Associated Invariant Chain
  • Gamma Chain Of Class II Antigens
  • HLA-DR-Gamma
  • II
  • CD74 Molecule
  • Ia-Associated Invariant Chain
  • Ii
  • CD74 Antigen
  • HLA Class II Histocompatibility Antigen Gamma Chain
  • CD74 Molecule, Major Histocompatibility Complex, Class II Invariant Chain

Description…

From NCBI Gene: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: CD74

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0