CCN2

Aliases
  • CCN family member 2
  • CCN2
  • CNN2
  • CTGF
  • HCS24
  • Hypertrophic chondrocyte-specific protein 24
  • IBP-8
  • IGF-binding protein 8
  • IGFBP-8
  • IGFBP8
  • Insulin-like growth factor-binding protein 8
  • MGC102839
  • NOV2
  • connective tissue growth factor
Description
CCN2, formerly known as CTGF, a major connective tissue mitoattractant secreted by vascular endothelial cells, promotes proliferation and differentiation of chondrocytes. It mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. It enhances fibroblast growth factor-induced DNA synthesis. CTGF is expressed in bone marrow and thymic cells. It is also expressed one of two Wilms tumors tested.
Attributes
QA State
Under Review
Type
Protein
HGNC Name
CCN2
Certifications
  • None
QA State for Ovary
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.