CCL2

Aliases
  • C-C motif chemokine 2
  • CCL2
  • GDCF-2
  • HC11
  • HSMCR30
  • MCAF
  • MCP-1
  • MCP1
  • MGC9434
  • Monocyte chemoattractant protein 1
  • Monocyte chemotactic and activating factor
  • Monocyte chemotactic protein 1
  • Monocyte secretory protein JE
  • SCYA2
  • SMC-CF
  • Small-inducible cytokine A2
  • chemokine (C-C motif) ligand 2
  • monocyte chemoattractant protein 1
  • monocyte chemoattractant protein-1
  • monocyte chemotactic and activating factor
  • monocyte chemotactic protein 1
  • monocyte secretory protein JE
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
  • small inducible cytokine subfamily A (Cys-Cys), member 2
  • small-inducible cytokine A2
Description
From NCBI Gene: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013]
Attributes
QA State
Curated
Type
Protein
HGNC Name
CCL2
Certifications
  • None
QA State for Breast
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.