CAPNS1
- Aliases
-
- 30K
- CALPAIN4
- CANP
- CANP small subunit
- CANPS
- CAPN4
- CAPNS
- CAPNS1
- CDPS
- CSS1
- Calcium-activated neutral proteinase small subunit
- Calcium-dependent protease small subunit
- Calcium-dependent protease small subunit 1
- Calpain regulatory subunit
- calcium-activated neutral proteinase small subunit
- calcium-dependent protease small subunit 1
- calcium-dependent protease, small subunit
- calpain 4, small subunit (30K)
- calpain regulatory subunit
- calpain small subunit 1
- calpain, small polypeptide
- calpain, small subunit 1
- Description
- From NCBI Gene: This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- CAPNS1
- Certifications
-
- None
- QA State for Lung
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.