CA9

Aliases:
This biomarker is also known as:
  • P54/58N
  • PMW1
  • MN
  • Carbonic Anhydrase IX
  • Carbonic Dehydratase
  • CAIX
  • RCC-Associated Protein G250
  • Membrane Antigen MN
  • RCC-Associated Antigen G250
  • Carbonic Anhydrase 9
  • EC 4.2.1.1
  • G250
  • Carbonate Dehydratase IX
  • CA9
  • Renal Cell Carcinoma-Associated Antigen G250
  • CA-IX

Description…

From NCBI Gene: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Genetic
HGNC Name:

The following organs have data associated with this biomarker…

Attributes

Phase: 2
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

No associated publications found.

Version 5.1.0