BMX

Aliases:
This biomarker is also known as:
  • EC 2.7.10.2
  • BMX
  • BMX non-receptor tyrosine kinase
  • EC 2.7.10
  • NTK38 tyrosine kinase
  • Bone marrow tyrosine kinase gene in chromosome X protein
  • PSCTK3
  • Etk/Bmx cytosolic tyrosine kinase
  • NTK38
  • Epithelial and endothelial tyrosine kinase
  • ETK
  • PSCTK2
  • cytoplasmic tyrosine-protein kinase BMX

Description…

BMX, or BMX non-receptor tyrosine kinase, belongs to the Tec kinase family. BMX, a non-receptor tyrosine kinase, plays a central but diverse modulatory role in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. The BMX protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: BMX

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0