ATF3

Aliases:
This biomarker is also known as:
  • cyclic AMP-dependent transcription factor ATF-3
  • cAMP-dependent transcription factor ATF-3
  • ATF3
  • activating transcription factor 3

Description…

ATF3 is a member of the the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. The ATF3 protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. the ATF3 gene is induced by many signals that are also involved in cancer cell signaling. ATF3 represses transcription from promoters with ATF sites. Several transcript variants encoding multiple isoforms have been found. It is thought that alternative splicing of this gene may be involved in the regulation of target genes.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: ATF3

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0