AP3B2
- Aliases
-
- AP-3 complex subunit beta-2
- AP3B2
- Adapter-related protein complex 3 subunit beta-2
- Adaptor protein complex AP-3 subunit beta-2
- Beta-3B-adaptin
- Clathrin assembly protein complex 3 beta-2 large chain
- NAPTB
- Neuron-specific vesicle coat protein beta-NAP
- Neuronal adaptin-like protein, beta-subunit
- adapter-related protein complex 3 subunit beta-2
- adaptor protein complex AP-3 subunit beta-2
- adaptor-related protein complex 3, beta 2 subunit
- beta-3B-adaptin
- clathrin assembly protein complex 3 beta-2 large chain
- neuron-specific vesicle coat protein beta-NAP
- Description
- From NCBI Gene: Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017]
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- AP3B2
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.