ADH5

Aliases
  • ADH-3
  • ADH5
  • ADHX
  • Alcohol dehydrogenase 5
  • Alcohol dehydrogenase class chi chain
  • Alcohol dehydrogenase class-III
  • EC 1.1.1.1,EC 1.1.1.-,EC 1.1.1.284
  • FALDH
  • FDH
  • GSH-FDH
  • GSNOR
  • Glutathione-dependent formaldehyde dehydrogenase
  • S-(hydroxymethyl)glutathione dehydrogenase
  • alcohol dehydrogenase (class III), chi polypeptide
  • alcohol dehydrogenase 5 (class III), chi polypeptide
  • alcohol dehydrogenase class chi chain
  • alcohol dehydrogenase class-3
  • alcohol dehydrogenase class-III
  • formaldehyde dehydrogenase
  • glutathione-dependent formaldehyde dehydrogenase
Description
From NCBI Gene: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]
Attributes
QA State
Curated
Type
Protein
HGNC Name
ADH5
Certifications
  • None
QA State for Breast
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.