Open Protocols

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Closed Protocols

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Publications

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Interests

The pattern of expression of TGF beta receptors and signal transducers

As has been previously shown for breast and head and neck tumors, the expression of TBR-II was greatly reduced in lung carcinomas. In addition, the expression of TGF-beta pathway-specific SMAD 2 was reduced. These data suggest that defects in the TGF- beta signaling pathway are common in lung carcinomas and could be exploited as potential markers.

The pattern of expression of TGF beta receptors and signal transducers

As has been previously shown for breast and head and neck tumors, the expression of TBR-II was greatly reduced in lung carcinomas. In addition, the expression of TGF-beta pathway-specific SMAD 2 was reduced. These data suggest that defects in the TGF- beta signaling pathway are common in lung carcinomas and could be exploited as potential markers.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Site

H. Lee Moffitt Cancer Center

Degree(s)

Ph.D.

Email

No email set

Fax

(813) 979-3893

Person ID

1170

EDRN Title

Co-Principal Investigator

Note

To update contact information, please visit the Data Management and Coordinating Center .