Open Protocols

Protocol Name	Investigatory Role	Biomarkers	Data Collections
Expansion of Enduring Infrastructure to Support Lung Cancer Screening Research	Leading	0	0
Indeterminate pulmonary nodule biomarker clinical utility trial	Involved	0	0
LTP2 Results Analysis-Schabath-Moffitt-2024	Leading	0	0
Radiomic Imaging Features and Epidemiology of Incidental Pulmonary Nodules	Leading	0	0
Validation of Molecular Biomarkers for the Early Detection of Lung Cancer in the setting of Indeterminate Pulmonary Nodules (Lung Team Project #2)	Involved	15	1

Closed Protocols

This person has no closed protocols at the present moment.

Publications

Publication Name	PubMed ID	Journal
A Radiogenomics Ensemble to Predict EGFR and KRAS Mutations in NSCLC.	33946756
Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer.	31417189	Br J Cancer
Application of Radiomics and Artificial Intelligence for Lung Cancer Precision Medicine.	33431509
Artificial intelligence in cancer imaging: Clinical challenges and applications.	30720861	CA Cancer J Clin
Calibrated Breast Density Measurements.	30545682	Acad Radiol
Cancer Progress and Priorities: Lung Cancer.	31575553	Cancer Epidemiol Biomarkers Prev
Comparison Between Radiological Semantic Features and Lung-RADS in Predicting Malignancy of Screen-Detected Lung Nodules in the National Lung Screening Trial.	29137847	Clin Lung Cancer
Delta radiomic features improve prediction for lung cancer incidence: A nested case-control analysis of the National Lung Screening Trial.	30507033	Cancer Med
Delta Radiomics Improves Pulmonary Nodule Malignancy Prediction in Lung Cancer Screening.	30607311	IEEE Access
Early-Life and Adult Anthropometrics in Relation to Mammographic Image Intensity Variation in the Nurses' Health Studies.	31826913	Cancer Epidemiol Biomarkers Prev
Evaluating clinical and radiomic features for predicting lung cancer recurrence pre- and post-tumor resection.	38993353
Explaining Deep Features Using Radiologist-Defined Semantic Features and Traditional Quantitative Features.	30854457	Tomography
Generalized breast density metrics.	30523909	Phys Med Biol
Habitats in DCE-MRI to Predict Clinically Significant Prostate Cancers.	30854444	Tomography
Images Are Data: Challenges and Opportunities in the Clinical Translation of Radiomics.	35661199
Integrated Biomarkers for the Management of Indeterminate Pulmonary Nodules.	34464235	Am J Respir Crit Care Med
Lung Cancer Screening Adherence Among People with HIV Treated at an Integrated Health System in Florida.	37132600
MILD trial, strong confirmation of lung cancer screening efficacy.	31118491	Nat Rev Clin Oncol
Multi-Window CT Based Radiological Traits for Improving Early Detection in Lung Cancer Screening.	33273859
Multi-window CT based Radiomic signatures in differentiating indolent versus aggressive lung cancers in the National Lung Screening Trial: a retrospective study.	31253194	Cancer Imaging
Novel clinical and radiomic predictors of rapid disease progression phenotypes among lung cancer patients treated with immunotherapy: An early report.	30797495	Lung Cancer
Optimal lung cancer screening intervals following a negative low-dose computed tomography result.	31632785	J Thorac Dis
Perfusion MR Imaging of Breast Cancer: Insights Using "Habitat Imaging".	29714676	Radiology
Predicting clinically significant prostate cancer using DCE-MRI habitat descriptors.	30647849	Oncotarget
Predicting malignant nodules by fusing deep features with classical radiomics features.	29594181	J Med Imaging (Bellingham)
Predicting Nodule Malignancy using a CNN Ensemble Approach.	30443438	Proc Int Jt Conf Neural Netw
Prediction of pathological nodal involvement by CT-based Radiomic features of the primary tumor in patients with clinically node-negative peripheral lung adenocarcinomas.	29624702	Med Phys
Qualitative Findings From a Survey on Patient Experiences and Satisfaction with Lung Cancer Screening.	36971270
Quantitative Imaging features Improve Discrimination of Malignancy in Pulmonary nodules.	31189944	Sci Rep
Radiologic Features of Small Pulmonary Nodules and Lung Cancer Risk in the National Lung Screening Trial: A Nested Case-Control Study.	28837413	Radiology
Radiological Image Traits Predictive of Cancer Status in Pulmonary Nodules.	27663588	Clin Cancer Res
Radiological semantics discriminate clinically significant grade prostate cancer.	31796094	Cancer Imaging
Radiomics of <sup>18</sup>F-FDG PET/CT images predicts clinical benefit of advanced NSCLC patients to checkpoint blockade immunotherapy.	31807885	Eur J Nucl Med Mol Imaging
Representation of Deep Features using Radiologist defined Semantic Features.	30443437	Proc Int Jt Conf Neural Netw
Revealing Tumor Habitats from Texture Heterogeneity Analysis for Classification of Lung Cancer Malignancy and Aggressiveness.	30872600	Sci Rep
Risk models to select high risk candidates for lung cancer screening.	29611557	Ann Transl Med
Risk of lung cancer in lung transplant recipients in the United States.	30565414	Am J Transplant
Stability and reproducibility of computed tomography radiomic features extracted from peritumoral regions of lung cancer lesions.	31494946	Med Phys
Technical challenges in generalizing calibration techniques for breast density measurements.	30525207	Med Phys

Interests

Validate image-based and radiomic biomarkers in lung including early detection

Conventional radiomics and end-to-end DL methods will be used to develop image-based diagnostics to differentiate between malignant and benign screening-detected and incidentally detected nodules

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Site

H. Lee Moffitt Cancer Center & Research Institute, Inc.

Degree(s)

Ph.D.

Email

matthew.schabath@moffitt.org

Person ID

3733

EDRN Title

EDRN Principal Investigator

Note

To update contact information, please visit the Data Management and Coordinating Center .