Schoen, Robert E.

Open Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Biomarkers of Risk for Colorectal Neoplasia (Team Project #2) Coordinating 0 0
Non-Invasive Testing for Advanced Adenomas Coordinating 0 0

Closed Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Preliminary Validation of Biomarkers for the Detection of Colorectal Adenomas (Team Project #1) Involved 1 0


Publication NamePubMed IDJournal
Assessing aneuploidy with repetitive element sequencing. 32075918 Proc Natl Acad Sci U S A
Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis. 21041628 Proc Natl Acad Sci U S A
Colorectal cancer prevention: Immune modulation taking the stage. 29391185 Biochim Biophys Acta Rev Cancer
Detection and localization of surgically resectable cancers with a multi-analyte blood test. 29348365 Science
Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs). 29432176 Proc Natl Acad Sci U S A
Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention. 32345712 Science
One year recurrence of aberrant crypt foci. 20570885 Cancer Prev Res (Phila)
PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. 21490394 J Clin Invest
Tumor DNA as a Cancer Biomarker through the Lens of Colorectal Neoplasia. 33033144 Cancer Epidemiol Biomarkers Prev


Colorectal Cancer Screening, Colon Cancer Biomarkers
Robert E. Schoen, M.D., M.P.H. is a Professor of Medicine and Epidemiology at the University of Pittsburgh and serves as Director of Colorectal and GI Cancer Prevention and Control Research for the University of Pittsburgh Cancer Institute. His research interests are in evaluating screening for colorectal cancer, encouraging use of screening tests, and in developing new biomarkers for early detection of cancer. He is the chair of the colorectal subcommittee for the NCI Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer screening trial, a randomized study of flexible sigmoidoscopy with over 154,000 participants. Dr. Schoen is evaluating intermediate biomarkers of colorectal cancer including endoscopic markers such as aberrant crypt foci, and serum markers based on nuclear matrix proteins.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Photograph of Schoen, Robert E.
University of Pittsburgh Cancer Institute
M.D., M.P.H
Person ID
EDRN Title
EDRN Principal Investigator
To update contact information, please visit the Data Management and Coordinating Center .