1:30-1:50pm

Platform discussion, Big Picture, Clinical Implications and Utility

1. How is technology evolving in relation to early detection of aggressive cancer?
2. Defining early detection applications - can technology identify “true precancer”? Early relapse and resistance detection?
3. Does current technology provide single cell resolution? Do we need single cell resolution?
4. Clinical implications?
5. Longitudinal sampling?

1:50-2:10pm

Technical Challenges of Implementing Spatial-Omics Technologies

1. Preanalytical considerations for tissue preparation (Fresh, OCT, FFPE?)
2. QA/QC considerations
3. Verification and validation of instruments
4. Validation of methods and assays – reproducibility, generalizability
5. Cost

2:10-2:30pm

Computational and Bioinformatics Challenges

1. Benchmarking new tools
2. QA/QC considerations
3. Verification and validation of bioinformatic pipelines
4. Development of user-friendly data visualization/analysis tools
5. Data sharing
6. Reproducibility of data across labs
7. Cost

2:30-3:00pm

Open Discussion

1. Establishment of knowledge Network (organ specific?)
2. Organizing working group
3. Generating collaborative projects ideas
4. Summary of round-table discussion