37th EDRN Steering Committee Meeting/EDRN Gastrointestinal Cancers Collaborative Group Meeting Draft Agenda

Tuesday, October 19, 2021

10 a.m. to 5:00 p.m. Eastern Daylight Time

Chair: Robert Schoen, MD, University of Pittsburgh

Co-chair: Brian Haab, PhD, Van Andel Research Institute

NCI Program Directors :   Jo Ann Rinaudo, PhD, and Matthew Young, PhD, National Cancer Institute

 

Agenda

 

EDRN GI Colon & Esophageal Group
 
Potential Clinical Utility Trial
10:00 a.m. – 10:45 a.m. Clinical Utility Studies
Moderator:
Sanford  Markowitz, MD, PhD, Case Western Reserve University
Discussion of Potential Clinical Utility Trials:
o   Clinical applications
o   Trial design
10:45 a.m. - 2:00 p.m. Team Projects and Core Funds

What was accomplished and what remains to be done
Feasibility of completion
Lessons learned
Recommendations for improvements
10:45  a.m. – 11:15 a.m. 01: Fred Hutch CVC Colon Cancer Marker Update
Paul Lampe, PhD, Fred Hutchinson Cancer Research Center
11:15 a.m. - 11:30 a.m. Q&A
11:30 a.m. – 11:45 a.m. 02: Case EDRN Team Projects Report
Helen Moinova, PhD, Case Western Reserve University
11:45 a.m. - 12:00 p.m. 03: Methylated Genes: Emerging Colon Adenoma Risk Prediction Biomarkers
William Grady, MD, Fred Hutchinson Cancer Research Center
12:00 p.m. - 12:15 p.m. Q&A for both presentations
12:15 p.m. - 12:30 p.m. Break
12:30 p.m. – 12:45 p.m. 04: Blood-based AA Detection
Cristian Tomasetti, PhD, The Johns Hopkins School of Medicine
12:45 p.m. - 1:00 p.m. 05: Morphomic Biomarkers of CRC Recurrence
o   Stewart Wang, MD, University of Michigan
o   Grace Su, MD, University of Michigan
1:00 p.m. - 1:15 p.m Q&A for both presentations
1:15 p.m. - 1:45 p.m. 06: GLNE
Robert Bresalier, MD, The University of Texas MD Anderson Cancer Center
1:45 p.m. - 2:00 p.m Q&A
EDRN GI PDAC Group
2:00 p.m. - 4:00 p.m. Team Projects and Core Funds

What was accomplished and what remains to be done
Feasibility of completion
Lessons learned
Recommendations for improvements
2:00  p.m. – 2:45 p.m. 07: Bake-off #1 and Bake-off # 2
Ying Huang, PhD, Fred Hutchinson Cancer Research Center
2:45 p.m. – 3:30 p.m. 08: Bake-off #3 (Presymptomatic and PLCO Samples)
Brian Haab, PhD, Van Andel Research Institute
3:30 p.m. – 3:45 p.m. 09: Update on Pancreatic Cyst Reference Set
Randy Brand, MD, University of Pittsburgh Medical Center
3:45 p.m. – 4:00 p.m. 10: Challenges and opportunities for radiomics and AI for early detection of pancreatic ductal adenocarcinoma (PDAC)
Eugene Koay, MD, PhD, The University of Texas MD Anderson Cancer Center
Potential Clinical Utility Trial
4:00 p.m. – 5:00 p.m. Clinical Utility Studies
Moderator: Anirban Maitra, MBBS, The University of Texas MD Anderson Cancer Center
Discussion of Potential Clinical Utility Trials:
o   Clinical applications
o   Trial design
5:00 p.m. Adjourn for the day