Taylor, Jeremy

Staff, University of Michigan,

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Open Protocols

Protocol Name	Biomarkers	Datasets
Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas Great Lakes New England (GLNE) Clinical Validation Center	0	0
Validation of Biomarkers for the Early Detection of Colorectal Adenocarcinoma (GLNE 010)	0	0
Clinical and Analytical Validation of Cancer Biomarkers: Developmental Studies	0	0
Clinical Validation of Molecular Signatures of Cervical Neoplasia	0	0
Detection of cancer DNA markers in urine	0	0
Using the methylome to identify aggressive Barrett’s esophagus	0	0

Closed Protocols

Protocol Name	Biomarkers	Datasets
GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett’s Esophagus Progression to Dysplasia and Adenocarcinoma	0	0
Preliminary Clinical Characterization of Serum Biomarkers for Colorectal Neoplasms	0	0
Preliminary Validation of Biomarkers for the Detection of Colorectal Adenomas (Team Project #1)	1	0
Standard Specimen Reference Set: Colon	0	0
EDRN Resource Network Exchange	0	0
Validation of Serum Markers for the Early Detection of Hepatocellular Carcinoma	3	0

Publications

Publication Name	PubMed ID	Journal
Gene amplification in esophageal adenocarcinomas and Barrett's with high-grade dysplasia.	14581353	Clin. Cancer Res.
Design of early validation trials of biomarkers.	19305629	Cancer Inform
Early detection of colon cancer: new tests on the horizon.	18422372	Mol Diagn Ther
Biomarkers for cancer risk, early detection, and prognosis: the validation conundrum.	17932336	Cancer Epidemiol. Biomarkers Prev.
Development of common data elements: the experience of and recommendations from the early detection research network.	12706181	Int J Med Inform
Missed adenomas during colonoscopic surveillance in individuals with Lynch Syndrome (hereditary nonpolyposis colorectal cancer).	19138994	Cancer Prev Res (Phila)
Detecting K-ras mutations in stool from fecal occult blood test cards in multiphasic screening for colorectal cancer.	17349741	Cancer Lett.
Multiplexed analysis of glycan variation on native proteins captured by antibody microarrays.	17417647	Nat. Methods
Chromoendoscopy detects more adenomas than colonoscopy using intensive inspection without dye spraying.	19139000	Cancer Prev Res (Phila)
Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis.	16117833	BMC Cancer
Rectal mucosal quantitative galactose oxidase-Schiff reaction as an early detection biomarker for colorectal cancer: comparison to fecal occult stool blood test.	21896998	Cancer Biomark
Pancreatic cancer serum detection using a lectin/glyco-antibody array method.	19072160	J. Proteome Res.
Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers.	22220206	PLoS ONE
Reliable gene expression measurements from fine needle aspirates of pancreatic tumors: effect of amplicon length and quality assessment.	20709792	J Mol Diagn
Molecular targets and clinical cancer risk reductive interventions.	21075336	Prog Mol Biol Transl Sci
An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer.	15289361	Cancer Res.
Microsatellite instability and DNA mismatch repair protein deficiency in Lynch syndrome colorectal polyps.	22262812	Cancer Prev Res (Phila)
Preferential isolation of fragmented DNA enhances the detection of circulating mutated k-ras DNA.	14709652	Clin. Chem.
CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma.	21169243	Clin. Cancer Res.
Detection of hypermethylated vimentin in urine of patients with colorectal cancer.	22251609	J Mol Diagn
Effect of cyclooxygenase genotype and dietary fish oil on colonic eicosanoids in mice.	21937210	J. Nutr. Biochem.
Molecular profiling of the immune response in colon cancer using protein microarrays: occurrence of autoantibodies to ubiquitin C-terminal hydrolase L3.	14595809	Proteomics
Breast cancer histology and receptor status characterization in Asian Indian and Pakistani women in the U.S.--a SEER analysis.	20459777	BMC Cancer
Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens.	15113102	J. Proteome Res.
Fecal DNA biomarkers for the detection of colorectal neoplasia: attractive, but is it feasible?	16077063	J. Natl. Cancer Inst.

To update protocols, publications, biomarkers, or science data, please contact the Informatics Center.

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