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Li, Christopher (M.D., Ph.D.)

PI, Fred Hutchinson Cancer Research Center, 206-667-7444

Contact Information

Email: mailto:cili@fredhutch.org
Fax:
EDRN Principal Investigator

To update contact information, please visit the Data Management and Coordinating Center.

Open Protocols

Protocol Name Biomarkers Datasets
Biomarkers to Distinguish Aggressive Cancers from Non-aggressive or Non-progressing Cancer 0 0
Breast Reference Set Application: Chris Li-FHCRC (2015) 0 0
DCIS Team Project 0 0
EDRN Breast and Ovary Cancer CVC, Study 1: Preliminary validation of breast cancer early detection biomarker candidates from our WHI discovery project 0 0
EDRN Breast and Ovary Cancer CVC, Study 2: Phase 3 retrospective validation of ovarian cancer early detection markers in serial preclinical samples from the PLCO trial 0 0
EDRN Breast and Ovary Cancer CVC, Study 3: Phase 3 Validation of screening decision rules in preclinical UKCTOCS serial samples 0 0
EDRN Breast and Ovary Cancer CVC, Study 4: Phase 3 Validation of Ovarian Cancer Serum Markers in Preclinical WHI Samples 0 0
Study 5: Phase 2 and 3 Validations of Putative Breast Cancer Early Detection Candidates 0 0
Benign Breast Disease Team Project 0 0
Validation of Early Detection Ovarian Cancer Biomarkers (Team Project) 149 0

Closed Protocols

Protocol Name Biomarkers Datasets
Breast Reference Set Application: Chris Li-FHCRC (2014) 0 0
Triple Negative Breast Cancer Team Project 77 0

Publications

Publication Name PubMed ID Journal
Identifying post-menopausal women at elevated risk for epithelial ovarian cancer. 26343159 Gynecol. Oncol.
Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections with Obesity. 27769113 J. Proteome Res.
Dermcidin expression is associated with disease progression and survival among breast cancer patients. 24562771 Breast Cancer Res. Treat.
Protein and glycomic plasma markers for early detection of adenoma and colon cancer. 27821646 Gut
Discovery of novel plasma proteins as biomarkers for the development of incisional hernias after midline incision in patients with colorectal cancer: The ColoCare study. 27745870 Surgery
JAK2 expression is associated with tumor-infiltrating lymphocytes and improved breast cancer outcomes: implications for evaluating JAK2 inhibitors. 24764577 Cancer Immunol Res
Longitudinal screening algorithm that incorporates change over time in CA125 levels identifies ovarian cancer earlier than a single-threshold rule. 23248253 J. Clin. Oncol.
Impact of screening test performance and cost on mortality reduction and cost-effectiveness of multimodal ovarian cancer screening. 22750949 Cancer Prev Res (Phila)
Designing early detection programs for ovarian cancer. 22180403 Ann. Oncol.
Interpretation of single and serial measures of HE4 and CA125 in asymptomatic women at high risk for ovarian cancer. 22962406 Cancer Epidemiol. Biomarkers Prev.
Potential role of HE4 in multimodal screening for epithelial ovarian cancer. 21917606 J. Natl. Cancer Inst.
Evaluation of ovarian cancer remission markers HE4, MMP7 and Mesothelin by comparison to the established marker CA125. 22155417 Gynecol. Oncol.
Candidate early detection protein biomarkers for ER+/PR+ invasive ductal breast carcinoma identified using pre-clinical plasma from the WHI observational study. 26319120 Breast Cancer Res. Treat.
Early-Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility? 27001493 Clin. Chem.

To update protocols, publications, biomarkers, or science data, please contact the Informatics Center.

Addresses

1100 Fairview Ave N M4-C308, P.O. Box 19024
Fred Hutchinson Cancer Research Center

To update addresses, please visit the Data Management and Coordinating Center.

32nd SC Meeting
Thank you to everyone who made the 32nd EDRN Steering Committee meeting a success. The next event is the 10th EDRN Scientific Workshop from March 6-8, 2018 in Bethesda, MD. More information about this Workshop will be sent soon. Click here to view the flyer.
Announcement



EDRN Founder Honored

Dr. Sudhir Srivastava was honored with the Distinguished Service Award from the American Pancreatic Association at the group's annual meeting this year, for his outstanding commitment to pancreatology.