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Malnik, Royceann

Staff, Fred Hutchinson Cancer Research Center, (206) 667-6972

Contact Information

Fax: 206-667-5964

To update contact information, please visit the Data Management and Coordinating Center.

Open Protocols

Protocol Name Biomarkers Datasets
A Methylation Panel for Bladder Cancer 0 0
Aurora Kinase A as a Biomarker for the Detection of Bladder Cancer - Supplemental Pre-Validation Protocol 0 0
Benign Breast Disease Team Project 0 0
Biomarkers for early detection of pancreatic cancer 0 1
Body Fluids as a Source of Diagnostic Biomarkers: Breast 0 0
Breast Reference Set Application: Chris Li-FHCRC (2015) 0 0
Breast Reference Set Application: GeorgeTuszynski-Temple (2012) 4 0
Breast Reference Set Application: Karen Anderson-ASU (2014) 0 0
BRSCW Reference Set Application: Michael Birrer-Massachusetts General Hospital (2013) 0 0
Canary TMA 13 0
Clinical and Analytical Validation of Cancer Biomarkers: Developmental Studies 0 0
Colon Reference Set Application: Robert Getzenberg - Johns Hopkins (2008) 2 0
Colon Reference Set Application: Moncef Jendoubi - Milagen (2006) 0 0
Colon Reference Set Application: Nam Kim - DiaDexus (2008) 0 0
DCIS Team Project 0 0
Development and Clinical Validation of Biomarkers for Prostate Cancer 0 0
Early Detection of Urinary Bladder Cancer 0 0
EDRN Breast and Ovary Cancer CVC, Study 1: Preliminary validation of breast cancer early detection biomarker candidates from our WHI discovery project 0 0
EDRN Pre-Validation of Metabolic Biomarkers of Prostate Cancer: Follow up EDRN Challenge 0 0
Hepatocellular carcinoma Early Detection Strategy study 0 0
Identification of biomarkers for lung cancer in never smokers 0 29
Liver Full Reference Set Application :Timothy Block - Drexel Univ (2010) 4 0
Liver Full Reference Set Application: David Lubman - Univ of Michigan (2011) 4 0
Lung Reference Set A Application: Pierre Massion-Vanderbilt (2017) 0 0
Pancreatic Cyst Biomarker Validation Study 0 0
Pancreatic Cystic Fluid Reference Set 0 0
Pancreatic Reference Set Application: Michael Hollingsworth-University of Nebraska (2014) 0 0
Pancreatic Reference Set Application: Samir Hanash-MD Anderson (2017) 0 0
PCA3 Reference Set Application: Samantha Maragh NIST 0 0
Prevalidation for Rectal PWS for Colon Cancer Screening 0 0
Prostate Active Surveillance Study 2 0
Proteomic Data Resources for EDRN Ovary Cancer Researchers within the EDRN 0 0
Protocol for Comparing Promoter Hypermethylation Methods in NSCLC 0 0
Upgrading Reference Set 0 0
Uterine Lavage 0 0
Utility of Biomarkers for Early Detection of Malignant Mesothelioma in a High-risk Population 0 0
Validation of Biomarkers for the Early Detection of Colorectal Adenocarcinoma (GLNE 010) 0 0
Validation of Early Detection Ovarian Cancer Biomarkers (Team Project) 149 0
Validation of Molecular Biomarkers for the Early Detection of Lung Cancer in the setting of Indeterminate Pulmonary Nodules (Lung Team Project #2) 0 0

Closed Protocols

Protocol Name Biomarkers Datasets
MALDI Dilution Data: Randolph 0 1
Barrett's Esophagus Methylation Profiles 11 1
Biomarker Reference Sets for Cancers in Women 0 0
Body Fluids as a Source of Diagnostic Biomarkers: Prostate 0 0
Breast Reference Set Application: Anu Mathew-Meso Scale (2012) 90 0
Breast Reference Set Application: Chris Li-FHCRC (2014) 0 0
Breast Reference Set Application: Karen Abbott- University of Arkansas (2013) 0 0
Breast Reference Set Application: Pinku Mukherjee-CanDiag (2014) 0 0
Breast Reference Set Application: Richard Zangar-PNNL (2012) 0 0
BRSCW Reference Set Application: Anna Lokshin - Univ of Pitts (2008) 0 0
BRSCW Reference Set Application: Anu Mathew - Meso Scale (2006) 0 0
BRSCW Reference Set Application: Eleftherios Diamandis - Mt Sinai (2006) 0 0
BRSCW Reference Set Application: GeorgeTuszynski - Temple University (2012) 0 0
BRSCW Reference Set Application: James Morre - NOX Technologies Inc. (2009) 0 0
BRSCW Reference Set Application: Joe Buechler - Biosite Inc (2009) 0 0
BRSCW Reference Set Application: Karen Abbott -University of Arkansas (2014) 0 0
BRSCW Reference Set Application: Michael Wilson - EIC Laboratories, Inc (2007) 0 0
Colon Reference Set Application: Mary Disis - University of Washington (2008) 0 0
Detection of Bladder CA by Microsatellite Analysis (MSA) 1 0
EDRN Resource Network Exchange 0 0
EDRN-WHI Pre-Clinical Colon Ca Specimens 0 9
Liver Full Reference Set Application: Hiro Yamada - Wako (2011) 3 0
Liver Rapid Reference Set Application ( #2): Lubman - Univ of Michigan (2010) 1 0
Liver Rapid Reference Set Application (#1): David Lubman - Univ of Michigan (2009) 1 0
Liver Rapid Reference Set Application (#1): Laura Beretta-FHCRC (2011) 0 0
Liver Rapid Reference Set Application (#2): Laura Beretta-FHCRC (2011) 0 0
Liver Rapid Reference Set Application: Gary Norman-INOVA (2012) 1 0
Liver Rapid Reference Set Application: Gianluigi Giannelli - Univ of Bari (2008) 6 0
Liver Rapid Reference Set Application: Hiro Yamada - Wako (2011) 2 0
Liver Rapid Reference Set Application: Kevin Qu-Quest (2011) 3 0
Liver Rapid Reference Set Application: Timothy Block - Drexel Univ (2008) 4 0
Lung Reference Set A Application: Edward Hirschowitz - University of Kentucky (2009) 0 0
Lung Reference Set A Application: Dawn Coverley- University of York (2011) 0 0
Lung Reference Set A Application: LaszloTakacs - Biosystems (2010) 0 0
Lung Reference Set A Application: Lee Goodglick/ Eleftherios Diamandis- UCLA/MSH (2009) 0 0
Lung Reference Set C Application: Rachel Ostroff - SomaLogics (2010) 13 0
Methylation & Proteomics-Based Detection of Bladder Cancer 0 0
MSA Bladder Reference Set Application: Charles Rosser-Hawaii (2014) 0 0
Pancreatic Reference Set Application- Ann Killary-MD Anderson (2012) 0 0
Pancreatic Reference Set Application: Brian Haab-Van Andel (2012) 2 0
Pancreatic Reference Set Application: Ivan Blasutig-University of Toronto (2014) 0 0
Pancreatic Reference Set Application: Kazufumi Honda-National Cancer Center (2014) 0 0
Pancreatic Reference Set Application: Surinder Batra- University of Nebraska (2014) 0 0
PCA3 Validation Study and Urinary Reference Set 2 0
Phase II Validation of a New Panel of Biomarkers for Early Detection of Ovarian Cancer 4 0
PLCO Ovarian Phase III Validation Study 50 1
Prostate Rapid Pre-Validation Set 6 0
Prostate Rapid Reference Set Application: Brian Haab - Van Andel (2006) 3 1
Prostate Rapid Reference Set Application: Daniel Chan/Patty Beckman- JHU/University of Minnesota (2007) 4 0
Prostate Rapid Reference Set Application: Eleftherios Diamandis - Mt Sinai (2006) 4 1
Prostate Rapid Reference Set Application: Robert Getzenberg - John Hopkins (2006) 0 0
Prostate Reference Set Application: proPSA-Dan Chan-JHU (2008) 2 0
Prostate Reference Set Application: William Isaacs-John Hopkins (2010) 0 0
Prostate Upgrading Team Project 0 0
SELDI Phase I: Assay Validation-Prostate 0 1
SELDI Validation Study Phase II 0 3
Soluble Mesothelin Related Peptide (SMRP) and Osteopontin (OPN) as Early Detection Markers for Malignant Mesothelioma (MM) 2 0
SPORE/EDRN/PRE-PLCO Ovarian Phase II Validation Study 55 2
Standard Specimen Reference Set: Breast Cancer and Imaging 0 0
Standard Specimen Reference Set: Liver 0 0
Standard Specimen Reference Set: Lung 0 0
Standard Specimen Reference Set: Pancreatic 0 0
Standard Specimen Reference Set: Prostate 0 0
Standard Specimen Reference Set: Colon 0 0
Triple Negative Breast Cancer Team Project 77 0
US-Turkey Cappadocia Mesothelioma Project 0 0
Validation of Protein Markers for Lung Cancer Using CARET Sera and Proteomics Techniques 6 1
Validation of Serum Markers for the Early Detection of Hepatocellular Carcinoma 3 0


Publication Name PubMed ID Journal
Selecting differentially expressed genes from microarray experiments. 12762450 Biometrics
Gauging the performance of SNPs, biomarkers, and clinical factors for predicting risk of breast cancer. 18612128 J. Natl. Cancer Inst.
Matching in studies of classification accuracy: implications for analysis, efficiency, and assessment of incremental value. 17501939 Biometrics
Evaluating the ROC performance of markers for future events. 18064569 Lifetime Data Anal
Design and estimation for evaluating principal surrogate markers in vaccine trials. 23409839 Biometrics
Net risk reclassification p values: valid or misleading? 24681599 J. Natl. Cancer Inst.
Pro-surfactant protein B as a biomarker for lung cancer prediction. 24248694 J. Clin. Oncol.
Letter by Pepe et al regarding article, "Use and misuse of the receiver operating characteristic curve in risk prediction". 17679623 Circulation
The risk of biopsy-detectable prostate cancer using the prostate cancer prevention Trial Risk Calculator in a community setting. 22552047 Urol. Oncol.
Polymorphisms in the glutathione S-transferase M1, T1, and P1 genes and prostate cancer prognosis. 16921513 Prostate
Combining results of microarray experiments: a rank aggregation approach. 17049026 Stat Appl Genet Mol Biol
Predicting time to prostate cancer recurrence based on joint models for non-linear longitudinal biomarkers and event time outcomes. 12483774 Stat Med
Glycosylation variants of mucins and CEACAMs as candidate biomarkers for the diagnosis of pancreatic cystic neoplasms. 20395854 Ann. Surg.
Boosting with missing predictors. 19948743 Biostatistics
Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation. 21363920 Cancer Res.
Classification versus association models: should the same methods apply? 20515278 Scand. J. Clin. Lab. Invest. Suppl.
Partial AUC estimation and regression. 14601762 Biometrics
Combining biomarkers to detect disease with application to prostate cancer. 14557109 Biostatistics
Phases of biomarker development for early detection of cancer. 11459866 J. Natl. Cancer Inst.
Insulin-like growth factor-I, insulin-like growth factor binding protein-3 and the risk of fibrocystic breast conditions among Chinese women. 16331609 Int. J. Cancer
Adopting nested case-control quota sampling designs for the evaluation of risk markers. 23807695 Lifetime Data Anal
Semiparametric models of time-dependent predictive values of prognostic biomarkers. 19397579 Biometrics
Semiparametric methods for evaluating risk prediction markers in case-control studies. 22822247 Biometrika
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 21424820 Eur. J. Epidemiol.
A practical multifaceted approach to selecting differentially expressed genes. 19455259 Cancer Inform
Adjusting for covariates in studies of diagnostic, screening, or prognostic markers: an old concept in a new setting. 18477651 Am. J. Epidemiol.
Borrowing Information across Populations in Estimating Positive and Negative Predictive Values. 22021938 J R Stat Soc Ser C Appl Stat
Performance of a single assay for both type III and type VI TMPRSS2:ERG fusions in noninvasive prediction of prostate biopsy outcome. 18948370 Clin. Chem.
Accommodating Covariates in ROC Analysis. 20046933 Stata J
Assessing the value of risk predictions by using risk stratification tables. 19017593 Ann. Intern. Med.
The potential of genes and other markers to inform about risk. 20160267 Cancer Epidemiol. Biomarkers Prev.
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 21407270 Eur. J. Hum. Genet.
Measuring the performance of markers for guiding treatment decisions. 21320940 Ann. Intern. Med.
Activated leukocyte cell adhesion molecule: a novel biomarker for breast cancer. 19322904 Int. J. Cancer
Clinical utility of five genetic variants for predicting prostate cancer risk and mortality. 19058137 Prostate
Conditional estimation of sensitivity and specificity from a phase 2 biomarker study allowing early termination for futility. 19097251 Stat Med
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. 21434890 Eur. J. Clin. Invest.
Adjusting for covariate effects on classification accuracy using the covariate-adjusted receiver operating characteristic curve. 22822245 Biometrika
A parametric ROC model-based approach for evaluating the predictiveness of continuous markers in case-control studies. 19459841 Biometrics
Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. 21414753 J Clin Epidemiol
Scale-based normalization of spectral data. 17192066 Cancer Biomark
Combining biomarkers linearly and nonlinearly for classification using the area under the ROC curve. 27058981 Stat Med
Ulcerative colitis is a disease of accelerated colon aging: evidence from telomere attrition and DNA damage. 18519043 Gastroenterology
Polymorphisms in steroid hormone biosynthesis genes and risk of breast cancer and fibrocystic breast conditions in Chinese women. 18483327 Cancer Epidemiol. Biomarkers Prev.
Model checking for ROC regression analysis. 17447940 Biometrics
Semiparametric estimation of time-dependent ROC curves for longitudinal marker data. 15475423 Biostatistics
Methods for Assessing Improvement in Specificity when a Biomarker is Combined with a Standard Screening Test. 20054437 Stat Biopharm Res
Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk. 18483343 Cancer Epidemiol. Biomarkers Prev.
Robust prediction of t-year survival with data from multiple studies. 20670303 Biometrics
Estimating the diagnostic likelihood ratio of a continuous marker. 20639522 Biostatistics
Genomic instability and copy-number heterogeneity of chromosome 19q, including the kallikrein locus, in ovarian carcinomas. 20800559 Mol Oncol
Nidogen-2: a new serum biomarker for ovarian cancer. 19883638 Clin. Biochem.
The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer. 19367279 Br. J. Cancer
Ultrasensitive detection and characterization of posttranslational modifications using surface-enhanced Raman spectroscopy. 16737206 Anal. Chem.
Comparing the predictive values of diagnostic tests: sample size and analysis for paired study designs. 16895044 Clin Trials
Assessing accuracy of mammography in the presence of verification bias and intrareader correlation. 15737102 Biometrics
Reproducible two-dimensional capillary electrophoresis analysis of Barrett's esophagus tissues. 16944874 Anal. Chem.
Telomere length in the colon declines with age: a relation to colorectal cancer? 16537718 Cancer Epidemiol. Biomarkers Prev.
Boosted decision tree analysis of surface-enhanced laser desorption/ionization mass spectral serum profiles discriminates prostate cancer from noncancer patients. 12324514 Clin. Chem.
Combining several screening tests: optimality of the risk score. 12230001 Biometrics
Re: "Clinical usefulness of the Framingham cardiovascular risk profile beyond its statistical performance: the Tehran Lipid and Glucose Study". 23524037 Am. J. Epidemiol.
Testing for improvement in prediction model performance. 23296397 Stat Med
Distribution-free ROC analysis using binary regression techniques. 12933607 Biostatistics
Estimating the receiver operating characteristic curve in studies that match controls to cases on covariates. 23601953 Acad Radiol
Presence of simian virus 40 DNA sequences in human lymphomas. 11897287 Lancet
Improving risk classification of critical illness with biomarkers: a simulation study. 23566734 J Crit Care
Estimating improvement in prediction with matched case-control designs. 23358916 Lifetime Data Anal
When does combining markers improve classification performance and what are implications for practice? 23348801 Stat Med
Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. 23254468 Lifetime Data Anal
Biases introduced by choosing controls to match risk factors of cases in biomarker research. 22730452 Clin. Chem.
On longitudinal prediction with time-to-event outcome: Comparison of modeling options. 27438160 Biometrics
The Early Detection Research Network's Specimen reference sets: paving the way for rapid evaluation of potential biomarkers. 23193062 Clin. Chem.
Evaluating the predictive value of biomarkers with stratified case-cohort design. 23173848 Biometrics
Further insight into the incremental value of new markers: the interpretation of performance measures and the importance of clinical context. 22875756 Am. J. Epidemiol.
A model for the design and construction of a resource for the validation of prognostic prostate cancer biomarkers: the Canary Prostate Cancer Tissue Microarray. 23232570 Adv Anat Pathol
The joint graphical lasso for inverse covariance estimation across multiple classes. 24817823 J R Stat Soc Series B Stat Methodol
Genetic variation in CYP19A1 and risk of breast cancer and fibrocystic breast conditions among women in Shanghai, China. 19064562 Cancer Epidemiol. Biomarkers Prev.
Comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by M. J. Pencina et al., Statistics in Medicine (DOI: 10.1002/sim.2929). 17671958 Stat Med
Personalized Evaluation of Biomarker Value: A Cost-Benefit Perspective. 27446505 Stat Biosci
The analysis of placement values for evaluating discriminatory measures. 15180681 Biometrics
Quantifying and comparing the accuracy of binary biomarkers when predicting a failure time outcome. 15122736 Stat Med
Standardizing diagnostic markers to evaluate and compare their performance. 16135934 Epidemiology
Can urinary PCA3 supplement PSA in the early detection of prostate cancer? 25385735 J. Clin. Oncol.
Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability. 22412972 PLoS ONE
Partly conditional survival models for longitudinal data. 16011684 Biometrics
Asymptotic Properties of the Sequential Empirical ROC, PPV and NPV Curves Under Case-Control Sampling. 24039313 Ann Stat
Semiparametric methods for evaluating the covariate-specific predictiveness of continuous markers in matched case-control studies. 21562626 J R Stat Soc Ser C Appl Stat
Increased plasma levels of the APC-interacting protein MAPRE1, LRG1, and IGFBP2 preceding a diagnosis of colorectal cancer in women. 22277732 Cancer Prev Res (Phila)
Identifying target populations for screening or not screening using logic regression. 15568185 Stat Med
Analysis of serum haptoglobin fucosylation in hepatocellular carcinoma and liver cirrhosis of different etiologies. 24807840 J. Proteome Res.
Identification of osteopontin as a novel marker for early hepatocellular carcinoma. 21953299 Hepatology
Quantifying and comparing the predictive accuracy of continuous prognostic factors for binary outcomes. 14744831 Biostatistics
Evaluating markers for selecting a patient's treatment. 15606407 Biometrics
Prediction of patient-specific risk and percentile cohort risk of pathological stage outcome using continuous prostate-specific antigen measurement, clinical stage and biopsy Gleason score. 20875091 BJU Int.
Immunohistochemical validation of expression microarray results. 15858137 J Mol Diagn
Identifying optimal biomarker combinations for treatment selection via a robust kernel method. 25124089 Biometrics
A new family-based association test via a least-squares method. 16451567 BMC Genet.
Application of Multidimensional Selective Item Response Regression Model for Studying Multiple Gene Methylation in SV40 Oncogenic Pathways. 19830254 J Am Stat Assoc
Assessing risk prediction models in case-control studies using semiparametric and nonparametric methods. 20527013 Stat Med
Signal detection in high-resolution mass spectrometry data. 18173224 J. Proteome Res.
Association of HPC2/ELAC2 polymorphisms with risk of prostate cancer in a population-based study. 14504198 Cancer Epidemiol. Biomarkers Prev.
Sample size calculations for comparative studies of medical tests for detecting presence of disease. 11870820 Stat Med
Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model. 12807723 Carcinogenesis
Vitamin D receptor gene polymorphisms and prostate cancer risk. 15065089 Prostate
Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker. 15105181 Am. J. Epidemiol.
A web-based system for managing and co-ordinating multiple multisite studies. 16279578 Clin Trials
Statistical considerations in combining biomarkers for disease classification. 15322313 Dis. Markers
Characterizing expected benefits of biomarkers in treatment selection. 25190512 Biostatistics
Improved Detection of Hepatocellular Carcinoma by Using a Longitudinal Alpha-Fetoprotein Screening Algorithm. 26260109 Clin. Gastroenterol. Hepatol.
Group sequential testing of the predictive accuracy of a continuous biomarker with unknown prevalence. 26537180 Stat Med
Two-stage biomarker panel study and estimation allowing early termination for futility. 25964662 Biostatistics
A statistical method for detecting differentially expressed SNVs based on next-generation RNA-seq data. 27276420 Biometrics
Improving the quality of biomarker discovery research: the right samples and enough of them. 25837819 Cancer Epidemiol. Biomarkers Prev.
Unbiased estimation of biomarker panel performance when combining training and testing data in a group sequential design. 26845527 Biometrics
A K-fold Averaging Cross-validation Procedure. 27630515 J Nonparametr Stat
Evaluating prognostic accuracy of biomarkers under competing risk. 22150576 Biometrics
Evaluating prognostic accuracy of biomarkers in nested case-control studies. 21856652 Biostatistics
Quantifying peptide signal in MALDI-TOF mass spectrometry data. 16195224 Mol. Cell Proteomics
Survival model predictive accuracy and ROC curves. 15737082 Biometrics
Evaluating technologies for classification and prediction in medicine. 16320261 Stat Med
Evaluating and comparing biomarkers with respect to the area under the receiver operating characteristics curve in two-phase case-control studies. 26883772 Biostatistics
Robust risk prediction with biomarkers under two-phase stratified cohort design. 27037494 Biometrics
Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease. 25471344 Cancer Epidemiol. Biomarkers Prev.
A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus. 19435894 Cancer Res.
Evaluation of matrix-assisted laser desorption/ionization-time of flight mass spectrometry proteomic profiling: identification of alpha 2-HS glycoprotein B-chain as a biomarker of diet. 15841498 Proteomics
Epidemiology informing clinical practice: from bills of mortality to population laboratories. 16341118 Nat Clin Pract Oncol
Detecting genomic aberrations using products in a multiscale analysis. 19817738 Biometrics
Prostate cancer specific mortality and Gleason 7 disease differences in prostate cancer outcomes between cases with Gleason 4 + 3 and Gleason 3 + 4 tumors in a population based cohort. 19836772 J. Urol.
Bias-reduced estimators and confidence intervals for odds ratios in genome-wide association studies. 18310059 Biostatistics
Statistical Aspects of the Use of Biomarkers in Nutritional Epidemiology Research. 19841649 Stat Biosci
Using the ROC curve for gauging treatment effect in clinical trials. 16220481 Stat Med
Optimized normalization for antibody microarrays and application to serum-protein profiling. 15793073 Mol. Cell Proteomics
Contrasting two frameworks for ROC analysis of ordinal ratings. 20147599 Med Decis Making
A sparse Ising model with covariates. 25099186 Biometrics
The sensitivity and specificity of markers for event times. 16079162 Biostatistics
Improving biomarker identification with better designs and reporting. 21666069 Clin. Chem.
Joint modeling, covariate adjustment, and interaction: contrasting notions in risk prediction models and risk prediction performance. 21968770 Epidemiology
New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization. 24124229 Cancer Discov
The optimal ratio of cases to controls for estimating the classification accuracy of a biomarker. 16428259 Biostatistics
Association of serum phospholipid fatty acids with breast cancer risk among postmenopausal cigarette smokers. 19255861 Cancer Causes Control
Prediction of ovarian cancer prognosis and response to chemotherapy by a serum-based multiparametric biomarker panel. 18766180 Br. J. Cancer
Estimating the capacity for improvement in risk prediction with a marker. 18714084 Biostatistics
Response. 25432412 J. Natl. Cancer Inst.
Integrated proteomic profiling of cell line conditioned media and pancreatic juice for the identification of pancreatic cancer biomarkers. 21653254 Mol. Cell Proteomics
FDR-controlling testing procedures and sample size determination for microarrays. 15977294 Stat Med
Estimating Risk with Time-to-Event Data: An Application to the Women's Health Initiative. 25018574 J Am Stat Assoc
Statistical issues in the evaluation of screening and early detection modalities. 18452826 Urol. Oncol.
Resampling Procedures for Making Inference under Nested Case-control Studies. 24436503 J Am Stat Assoc
Combining predictors for classification using the area under the receiver operating characteristic curve. 16542249 Biometrics
A regularized multivariate regression approach for eQTL analysis. 26085849 Stat Biosci
Does the net reclassification improvement help us evaluate models and markers? 24592500 Ann. Intern. Med.
Application of the time-dependent ROC curves for prognostic accuracy with multiple biomarkers. 16542256 Biometrics
Measures to summarize and compare the predictive capacity of markers. 20224632 Int J Biostat
Conditional estimation after a two-stage diagnostic biomarker study that allows early termination for futility. 22238117 Stat Med
Time-dependent Predictive Values of Prognostic Biomarkers with Failure Time Outcome. 19655041 J Am Stat Assoc
Insights into latent class analysis of diagnostic test performance. 17085745 Biostatistics
Analyzing LC-MS/MS data by spectral count and ion abundance: two case studies. 24163717 Stat Interface
Efficient use of longitudinal CD4 counts and viral load measures in survival analysis. 22415871 Stat Med
Commentary: Reporting standards are needed for evaluations of risk reclassification. 21571811 Int J Epidemiol
Statistical Methods for Tissue Array Images - Algorithmic Scoring and Co-training. 22984376 Ann Appl Stat
Assessing the diagnostic accuracy of a sequence of tests. 12925502 Biostatistics
Prevalidation of salivary biomarkers for oral cancer detection. 22301830 Cancer Epidemiol. Biomarkers Prev.
Biomarker evaluation and comparison using the controls as a reference population. 18755739 Biostatistics
Pivotal evaluation of the accuracy of a biomarker used for classification or prediction: standards for study design. 18840817 J. Natl. Cancer Inst.
Assessing treatment-selection markers using a potential outcomes framework. 22299708 Biometrics
Evaluating the predictiveness of a continuous marker. 17489968 Biometrics
Prospective accuracy for longitudinal markers. 17688486 Biometrics
Problems with risk reclassification methods for evaluating prediction models. 21555714 Am. J. Epidemiol.
Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women. 17624589 Breast Cancer Res. Treat.
Cruciferous vegetable supplementation in a controlled diet study alters the serum peptidome in a GSTM1-genotype dependent manner. 21272319 Nutr J
Structured penalties for functional linear models-partially empirical eigenvectors for regression. 22639702 Electron J Stat

To update protocols, publications, biomarkers, or science data, please contact the Informatics Center.


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Fred Hutchinson Cancer Research Center

To update addresses, please visit the Data Management and Coordinating Center.


EDRN Founder Honored

Dr. Sudhir Srivastava was honored with the Distinguished Service Award from the American Pancreatic Association at the group's annual meeting this year, for his outstanding commitment to pancreatology.