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Roy, Hemant K. (M.D.)

PI, Boston University, 847-657-1900

Contact Information

Fax: 847-733-5041
EDRN Associate Member

To update contact information, please visit the Data Management and Coordinating Center.

Open Protocols

Protocol Name Biomarkers Datasets
Prevalidation for Rectal PWS for Colon Cancer Screening 0 0
Spectral Markers for Early Detection of Colon Neoplasia 0 0
Light Scattering Spectroscopy for the Detection of Colorectal Neoplasia 0 0

Closed Protocols

No closed protocols.


Publication Name PubMed ID Journal
The association between aspirin use and the incidence of colorectal cancer in women. 16847042 Am. J. Epidemiol.
Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/beta-catenin signaling. 16928827 Mol. Cancer Ther.
Practicing medicine at the front lines of the genomic revolution. 16157823 Arch. Intern. Med.
Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling: Influence of smoking. 16874859 World J. Gastroenterol.
Low-coherent backscattering spectroscopy for tissue characterization. 15717826 Appl Opt
Depth-resolved low-coherence enhanced backscattering. 15832924 Opt Lett
Assessment of blood supply in superficial tissue by polarization-gated elastic light-scattering spectroscopy. 16422163 Appl Opt
Spectral markers in preneoplastic intestinal mucosa: an accurate predictor of tumor risk in the MIN mouse. 16030095 Cancer Epidemiol. Biomarkers Prev.
The transcriptional repressor SNAIL is overexpressed in human colon cancer. 15712635 Dig. Dis. Sci.
Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation. 15961079 FEBS Lett.
Associations between the age at diagnosis and location of colorectal cancer and the use of alcohol and tobacco: implications for screening. 16567601 Arch. Intern. Med.
Polyethylene glycol inhibits intestinal neoplasia and induces epithelial apoptosis in Apc(min) mice. 15374630 Cancer Lett.
Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: modulation of apoptosis, proliferation, and fractal dimension. 15367710 Mol. Cancer Ther.
Four-dimensional elastic light-scattering fingerprints as preneoplastic markers in the rat model of colon carcinogenesis. 15057746 Gastroenterology
Risk stratification of colon carcinogenesis through enhanced backscattering spectroscopy analysis of the uninvolved colonic mucosa. 16467111 Clin. Cancer Res.
Tobacco use and increased colorectal cancer risk in patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome). 15596632 Arch. Intern. Med.
The nonsteroidal anti-inflammatory drug, nabumetone, differentially inhibits beta-catenin signaling in the MIN mouse and azoxymethane-treated rat models of colon carcinogenesis. 15617833 Cancer Lett.
Increased microvascular blood content is an early event in colon carcinogenesis. 15831911 Gut
Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis. 21493000 Cancer Lett.
Optical detection of buccal epithelial nanoarchitectural alterations in patients harboring lung cancer: implications for screening. 20924114 Cancer Res.
Colonoscopy and optical biopsy: bridging technological advances to clinical practice. 21521641 Gastroenterology
Involvement of p21cip1/waf1 in the anti-proliferative effects of polyethylene glycol in colon carcinogenesis. 21170505 Int. J. Oncol.
Light-scattering technologies for field carcinogenesis detection: a modality for endoscopic prescreening. 21078318 Gastroenterology
Association of stem-like cells in gender-specific chemoprevention against intestinal neoplasia in MIN mouse. 21769438 Oncol. Rep.
Optical measurement of rectal microvasculature as an adjunct to flexible sigmoidosocopy: gender-specific implications. 20570881 Cancer Prev Res (Phila)
Nanocytology for field carcinogenesis detection: novel paradigm for lung cancer risk stratification. 21174531 Future Oncol
Moving toward personalization of colorectal cancer screening: Comment on "Influence of race and sex on prevalence and recurrence of colon polyps". 20625019 Arch. Intern. Med.
Biomarkers for the early detection of cancer: an inflammatory concept. 17893302 Arch. Intern. Med.
Colon cancer screening: the good, the bad, and the ugly. 17101934 Arch. Intern. Med.
Low-coherence enhanced backscattering: review of principles and applications for colon cancer screening. 16965153 J Biomed Opt
Inducible nitric oxide synthase (iNOS) mediates the early increase of blood supply (EIBS) in colon carcinogenesis. 17658518 FEBS Lett.
Optical markers in duodenal mucosa predict the presence of pancreatic cancer. 17671121 Clin. Cancer Res.

To update protocols, publications, biomarkers, or science data, please contact the Informatics Center.


Evanston Hospital, 2650 Ridge Avenue, G208
Boston University

To update addresses, please visit the Data Management and Coordinating Center.

Announcement 10/23/2017

Three new FOAs on the Human Tumor Atlas and associated with the Cancer Moonshot Initiative have been released. Please click here for more information.

10th Science Workshop
Thank you to everyone who made the 32nd EDRN Steering Committee meeting a success. The next event is the 10th EDRN Scientific Workshop from March 6-8, 2018 in Bethesda, MD. Click to view the flyer; click to visit the registration page.
EDRN Founder Honored

Dr. Sudhir Srivastava was honored with the Distinguished Service Award from the American Pancreatic Association at the group's annual meeting this year, for his outstanding commitment to pancreatology.