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Haab, Brian (Ph.D.)

PI, Van Andel Research Institute, 616-234-5268

Contact Information

Email: mailto:brian.haab@vai.org
Fax:
EDRN Principal Investigator

To update contact information, please visit the Data Management and Coordinating Center.

Open Protocols

Protocol Name Biomarkers Datasets
A Biomarker Bakeoff in Early Stage Pancreatic Cancer 0 0
Biomarkers for the Early Detection of Pancreatic Cancer 0 0
Pancreatic Cyst Biomarker Validation Study 0 0

Closed Protocols

Protocol Name Biomarkers Datasets
Pancreatic Reference Set Application: Brian Haab-Van Andel (2012) 2 0
Prostate Rapid Reference Set Application: Brian Haab - Van Andel (2006) 3 1
Early Diagnosis of Pancreatic Cancer-Network Collaborative Studies 0 0
Prostate Rapid Pre-Validation Set 6 0

Publications

Publication Name PubMed ID Journal
Glycans related to the CA19-9 antigen are elevated in distinct subsets of pancreatic cancers and improve diagnostic accuracy over CA19-9. 26998508 Cell Mol Gastroenterol Hepatol
Segment and fit thresholding: a new method for image analysis applied to microarray and immunofluorescence data. 26339978 Anal. Chem.
A Gastric Glycoform of MUC5AC Is a Biomarker of Mucinous Cysts of the Pancreas. 27992432 PLoS ONE
Mining High-Complexity Motifs in Glycans: A New Language To Uncover the Fine Specificities of Lectins and Glycosidases. 29058413 Anal. Chem.
Definitive Characterization of CA 19-9 in Resectable Pancreatic Cancer Using a Reference Set of Serum and Plasma Specimens. 26431551 PLoS ONE
Identification of blood-protein carriers of the CA 19-9 antigen and characterization of prevalence in pancreatic diseases. 21751362 Proteomics
Comparison of surgical and endoscopic sample collection for pancreatic cyst fluid biomarker identification. 22439797 J. Proteome Res.
Chemically-blocked antibody microarray for multiplexed high-throughput profiling of specific protein glycosylation in complex samples. 22588202 J Vis Exp
Upregulation of glycans containing 3' fucose in a subset of pancreatic cancers uncovered using fusion-tagged lectins. 25938165 J. Proteome Res.
Characterization of glycoproteins in pancreatic cyst fluid using a high-performance multiple lectin affinity chromatography platform. 24303806 J. Proteome Res.
Determining lectin specificity from glycan array data using motif segregation and GlycoSearch software. 23839995 Curr Protoc Chem Biol
Using antibody arrays to measure protein abundance and glycosylation: considerations for optimal performance. 24510592 Curr Protoc Protein Sci
Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts. 23836919 Mol. Cell Proteomics
The detection and discovery of glycan motifs in biological samples using lectins and antibodies: new methods and opportunities. 25727148 Adv. Cancer Res.
Glycan motif profiling reveals plasma sialyl-lewis x elevations in pancreatic cancers that are negative for sialyl-lewis A. 25733690 Mol. Cell Proteomics
Modulation of glycan detection on specific glycoproteins by lectin multimerization. 23286506 Anal. Chem.
Using lectins in biomarker research: addressing the limitations of sensitivity and availability. 22927350 Proteomics Clin Appl
The fine specificity of mannose-binding and galactose-binding lectins revealed using outlier motif analysis of glycan array data. 21875884 Glycobiology
High-throughput studies of protein glycoforms using antibody-lectin sandwich arrays. 21901603 Methods Mol. Biol.
Global comparisons of lectin-glycan interactions using a database of analyzed glycan array data. 23399549 Mol. Cell Proteomics
Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation. 22623153 Proteomics
Prediction of glycan motifs using quantitative analysis of multi-lectin binding: Motifs on MUC1 produced by cultured pancreatic cancer cells. 23956151 Proteomics Clin Appl
Cyst fluid interleukin-1beta (IL1beta) levels predict the risk of carcinoma in intraductal papillary mucinous neoplasms of the pancreas. 21266527 Clin. Cancer Res.
The development of an integrated platform to identify breast cancer glycoproteome changes in human serum. 19782370 J Chromatogr A
The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. 28642461 Sci Rep
Characterizing Protein Glycosylation through On-Chip Glycan Modification and Probing. 27809484 Anal. Chem.
The Marker State Space (MSS) method for classifying clinical samples. 23750276 PLoS ONE

To update protocols, publications, biomarkers, or science data, please contact the Informatics Center.

Addresses

333 Bostwick Avenue, N.E.
Van Andel Research Institute

To update addresses, please visit the Data Management and Coordinating Center.

Announcement 03/14/2018
Thank you to everyone to made the 10th EDRN Scientific Workshop a success. The next event is the 33rd EDRN Steering Committee Meeting from September 5-6, 2018 in Boston, MA. Details will be available soon.


Three new FOAs on the Human Tumor Atlas and associated with the Cancer Moonshot Initiative have been released. Please click here for more information.

Announcement 10/23/2017

Three new FOAs on the Human Tumor Atlas and associated with the Cancer Moonshot Initiative have been released. Please click here for more information.

EDRN Founder Honored

Dr. Sudhir Srivastava was honored with the Distinguished Service Award from the American Pancreatic Association at the group's annual meeting this year, for his outstanding commitment to pancreatology.