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Designing early detection programs for ovarian cancer.

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Ann. Oncol.. 2011 Dec 22 Suppl 8 ().

Human epididymis protein 4 (HE4) shows promise as a serum marker that complements CA125 in the early detection of epithelial ovarian cancer, either as a first-line screen or as a second-line screen in a multimodal strategy. Incorporation of symptoms in a screening strategy that includes CA125 and HE4 may warrant further research.

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