You are here: Home / Publications / Proteomic analysis of cancer-cell mitochondria.

Proteomic analysis of cancer-cell mitochondria.

14570046

Nat. Rev. Cancer. 2003 10 3 (10).

Mitochondrial dysfunction and mutations in mitochondrial DNA have been frequently reported in cancer cells. Mitochondrial gene-expression signatures of transformed cells have been identified; however, the phenotypic effects of these genetic alterations remain to be established. Identification of mitochondrial proteins that are aberrantly expressed in cancer cells has been made possible by the recent development of mitochondrial functional proteomics and could identify new markers for early detection and risk assessment, as well as targets for therapeutic intervention.

This icon signifies that something is happening and we kindly ask you to please wait