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EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.


Title Abstract Investigator
EDRN Resource Network Exchange Create a distributed on-line virtual specimen repository. Srivastava, Sudhir
EDRN-WHI Pre-Clinical Colon Ca Specimens Specifically, it is proposed to assess plasma proteins from postmenopausal women diagnosed with colon cancer within a span of 18 months after year-3 OS blood ... Hanash, Samir
Early Detection Research Network Registry for Hereditary Cancer The EDRN High Risk Registry (HRR)recruits individuals that carry germline mutations for hereditary cancer syndromes, who are willing to participate in ... Lynch, Henry
Early Detection of Breast Cancer Using Autoantibody Markers To identify large numbers of antigens that can be used to recognize the presence of cancer by detecting antibodies to tumor proteins in the serum of the test ... Tainsky, Michael A.
Early Detection of Cancer by Affinity Mass Spectrometry-Set Aside funds A.   RATIONALE The recent introduction of multiple reaction monitoring capabilities offers unprecedented capability to the research arsenal available to ... Semmes, John
Early Detection of Urinary Bladder Cancer Czerniak, Bogdan
Early Diagnosis of Pancreatic Cancer-Network Collaborative Studies Determining and quantifying the types of mucin core proteins to which CA19-9 is attached will result in assays with improved performance characteristics ... Hollingsworth, Michael
Early Molecular Detection of Invasive Bladder Cancer by Urine Examination Czerniak, Bogdan
Early detection of liver cancer and hepatitis Block, Timothy
Ecogenetic Study of Lung Cancer Spitz, Margaret R.
Establishment of a serum standard for use in high-throughput proteomic Semmes, John
Evaluating DNA Damage and DNA Repair Capacity as Biomarkers of Non- Indolent Prostate Cancer Nelson, Peter S
Evaluating SelectMDx for the prediction of high-grade prostate cancer in men with low-grade prostate cancer on active surveillance in the Canary Prostate Active Surveillance Study (PASS) The need for repeated biopsy is a major downside of active surveillance, and can lead to patients opting for definitive treatment or, conversely, declining to ... Lin UW, Daniel W.
Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas Great Lakes New England (GLNE) Clinical Validation Center Brenner, Dean
Evaluation of emerging tissue-based biomarkers for aggressive prostate cancer in men on active surveillance This work is being done as part of the funded NIH grant entitled Precision Medicine Approach to Prostate Cancer Active Surveillance (R01 CA184712; PD-PIs Mark ... Mosquera, Juan Miguel
Evaluation of tissue biomarker of Urologic cancer, including prostate, bladder and kidneys using surplus human tissues Chinnaiyan, Arul M.
Expansion of Enduring Infrastructure to Support Lung Cancer Screening Research Schabath, Matthew
Expression based markers for breast cancer detection Marks, Jeffrey
GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett’s Esophagus Progression to Dysplasia and Adenocarcinoma    Recognizing that novel potential biomarkers are continually being identified and will need to be validated in a rapid, efficient, and scientifically ... Brenner, Dean
GSTP1 Methylation Sidransky, David
Germline Genetic Variants and Faliure of Acitve Sureveillance Study the impact of germline genetic variants on Active Surveillance (AS) failure. Information will help develop methods for identifying men with low-risk PC ... Lin UW, Daniel W.
Glycoprotein Biomarkers for the Early Detection of Aggressive Prostate Cancer The Early Detection Research Network of the NCI is charged with the discovery, development and validation of biomarkers for early detection and prognosis ... Zhang, Hui L.
HNPCC colon cancer-associated SELDI mass spectrometry protein profiles in serum Lynch, Henry
Hepatocellular carcinoma Early Detection Strategy study Part 1: The first part of this study is to conduct follow-up for patients that were enrolled in the EDRN Phase 2 Validation Study called DCP (13). For this ... Marrero, Jorge
Hereditary Cancer Institute family study specimen bank Lynch, Henry
High-Throughput Evaluation of Breast Cancer Markers The objective of this study is to use a combination of AMT proteomics and ELISA microarray testing to discover and validate novel biomarkers for breast cancer. Zangar, Richard (Rick) C.
Hollingsworth - Aggressive vs Indolent 2012 Study Overview. We will examine DNA extracted from FFPE sections from approximately 200 different surgically resected primary pancreatic tumors from the UNMC ... Hollingsworth, Michael
Identification of New Markers in Normal and Abnormal Pap Smears Unger, Elizabeth R.
Identification of Novel Cancer Biomarkers in Serum and Urine Specimens Chinnaiyan, Arul M.
Identification of biomarkers for ER+ breast cancer Validate clinically useful early detection biomarkers specific to ER+ breast cancer Li, Christopher
Announcement 09/27/2019
Thank you to everyone who made the 11th EDRN Scientific Workshop a success. The next EDRN Steering Committee Meeting is from Tuesday-Thursday, March 31-April 2, 2020 in Tempe, AZ.

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