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EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.


Title Abstract Investigator
Early Detection Research Network Registry for Hereditary Cancer The EDRN High Risk Registry (HRR)recruits individuals that carry germline mutations for hereditary cancer syndromes, who are willing to participate in ... Lynch, Henry
Early Detection and Prognosis of Hepatocellular Carcinoma Volk, Michael L.
Early Detection of Breast Cancer Using Autoantibody Markers To identify large numbers of antigens that can be used to recognize the presence of cancer by detecting antibodies to tumor proteins in the serum of the test ... Tainsky, Michael A.
Early Detection of Cancer by Affinity Mass Spectrometry-Set Aside funds A.   RATIONALE The recent introduction of multiple reaction monitoring capabilities offers unprecedented capability to the research arsenal available to ... Semmes, John
Early Detection of Urinary Bladder Cancer Czerniak, Bogdan
Early Diagnosis of Pancreatic Cancer-Network Collaborative Studies Determining and quantifying the types of mucin core proteins to which CA19-9 is attached will result in assays with improved performance characteristics ... Hollingsworth, Michael
Early Molecular Detection of Invasive Bladder Cancer by Urine Examination Czerniak, Bogdan
Early detection of liver cancer and hepatitis Block, Timothy
Ecogenetic Study of Lung Cancer Spitz, Margaret R.
Establishment of a serum standard for use in high-throughput proteomic Semmes, John
Expression based markers for breast cancer detection Marks, Jeffrey
GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett’s Esophagus Progression to Dysplasia and Adenocarcinoma    Recognizing that novel potential biomarkers are continually being identified and will need to be validated in a rapid, efficient, and scientifically ... Brenner, Dean
GSTP1 Methylation Sidransky, David
Glycoprotein Biomarkers for the Early Detection of Aggressive Prostate Cancer The Early Detection Research Network of the NCI is charged with the discovery, development and validation of biomarkers for early detection and prognosis ... Zhang, Hui L.
HNPCC colon cancer-associated SELDI mass spectrometry protein profiles in serum Lynch, Henry
Hepatocellular carcinoma Early Detection Strategy study Part 1: The first part of this study is to conduct follow-up for patients that were enrolled in the EDRN Phase 2 Validation Study called DCP (13). For this ... Marrero, Jorge
Hereditary Cancer Institute family study specimen bank Lynch, Henry
High-Throughput Evaluation of Breast Cancer Markers The objective of this study is to use a combination of AMT proteomics and ELISA microarray testing to discover and validate novel biomarkers for breast cancer. Zangar, Richard (Rick) C.
Hollingsworth - Aggressive vs Indolent 2012 Study Overview. We will examine DNA extracted from FFPE sections from approximately 200 different surgically resected primary pancreatic tumors from the UNMC ... Hollingsworth, Michael
Hollingsworth - Aggressive vs Indolent 2012 (357) Study Overview. We will examine DNA extracted from FFPE sections from approximately 200 different surgically resected primary pancreatic tumors from the UNMC ... Hollingsworth, Michael
Hollingsworth - Aggressive vs Indolent 2012 (359) Hollingsworth, Michael
Identification of New Markers in Normal and Abnormal Pap Smears Unger, Elizabeth R.
Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer. BACKGROUND: Lung cancer is the leading cause of cancer death in men and women in the United States and Western Europe. Over 160,000 Americans die of this ... Anglim, Paul
Identification of biomarkers for lung cancer in never smokers The overall goal of this project is to identify, verify and apply biomarkers for the early diagnosis or risk assessment of lung cancer in never smokers. The ... Gazdar, Adi
Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer. Gene expression profile analysis of lung cancers revealed the transactivation of an immunoglobulin-like molecule Nectin-4 in the majority of non-small cell ... Takano, Atsushi
Identification of protein and genetic biomarkers of prostate cancer and risk factors for progression of disease Thompson, Ian M.
Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis The detection of nonsmall cell lung cancer (NSCLC) at an early stage presents a daunting challenge due to the lack of a specific noninvasive marker. The ... Chen, Xi
In-depth proteomic analysis of non-small cell lung cancer to discover molecular targets and candidate biomarkers Advances in proteomic analysis of human samples are driving critical aspects of biomarker discovery and the identification of molecular pathways involved in ... Carbone, David P
Inflammation as a Potential Marker of Risk ad Progression for Prostate Cancer Thompson, Ian M.
Integrated Development of Novel Molecular Markers Sidransky, David
2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.