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EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.


Title Abstract Investigator
Liver Rapid Reference Set Application: Gary Norman-INOVA (2012) We have developed a new and novel assay for the detection of Golgi protein 73 (GP73), also known as Golgi membrane protein 1 (Golm1) or Golgi phosphoprotein 2 ... Norman, Gary L.
Liver Rapid Reference Set Application: Gianluigi Giannelli - Univ of Bari (2008) To evaluate biomarker performance in an out-side cohort of LC and HCC patients Giannelli, Gianluigi
Liver Rapid Reference Set Application: Hemken - Abbott (2015) The aim for this testing is to find a small panel of biomarkers (n=2-5) that can be tested on the Abbott ARCHITECT automated immunoassay platform for the early ... Hemken, Philip M
Liver Rapid Reference Set Application: Hiro Yamada - Wako (2011) Measure clinical effectiveness of AFP-L3 and DCP for early detection of HCC in patient samples collected prospectively during surveillance. However since such ... Yamada, Hiro
Liver Rapid Reference Set Application: Kevin Qu-Quest (2011) We propose to evaluate the performance of a novel serum biomarker panel for early detection of hepatocellular carcinoma (HCC). This panel is based on markers ... Qu, Kevin
Liver Rapid Reference Set Application: Timothy Block - Drexel Univ (2008) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Lung Reference Set A Application: Edward Hirschowitz - University of Kentucky (2009) We are continuing validation with two advanced objectives: 1) To evaluate assay performance for established lung cancer diagnosed in a clinical population 2) ... Hirschowitz, Edward
Lung Reference Set A Application: Dawn Coverley- University of York (2011) A variant of the nuclear matrix factor Ciz1 is prevalent in lung cancer cell lines and tumours, but not in adjacent lung tissue, giving rise to a protein that ... Coverley, Dawn
Lung Reference Set A Application: LaszloTakacs - Biosystems (2010) We would like to access the NCI lung cancer Combined Pre-Validation Reference Set A in order to further validate a lung cancer diagnostic test candidate. Our ... Takacs, Laszlo
Lung Reference Set A Application: Lee Goodglick/ Eleftherios Diamandis- UCLA/MSH (2009) To study of the utility of KLK8, 11, 12, 13, and 14 profiles in diagnosing lung cancer. Chia, David
Lung Reference Set A Application: Pierre Massion-Vanderbilt (2017) Massion, Pierre
Lung Reference Set C Application: Rachel Ostroff - SomaLogics (2010) Analysis of the EDRN lung biomarker samples will enable the next step in development of a clinical diagnostic assay for the differential diagnosis of lung ... Ostroff, Rachel
MALDI Dilution Data: Randolph Feng, Ziding
MMR protein expression in HNPCC Lynch, Henry
MSA Bladder Reference Set Application: Charles Rosser-Hawaii (2014) The goal of this proposal is straightforward. We wish to assay in a discovery set, reference set from EDRN, both PAI-1 and ANG promoters and genes for ... Rosser, Charles J
Methylation & Proteomics-Based Detection of Bladder Cancer Study never Launched Cairns, Paul
Methylation tumor markers in HNPCC Lynch, Henry
Molecular Basis of Barrett's -Associated Carcinogenesis Stass, Sanford
Molecular Genetics of Urinary Bladder Carcinoma Czerniak, Bogdan
Molecular Progression of Methylation in Bladder Cancer Sidransky, David
Mutational load distribution analysis (MLDA) in pancreatic cancer Certain p16 mutation carriers showed mutation elevations in the specific Ki-ras and p53 alleles significantly higher than normal, similar to controls with ... Lynch, Henry
NYU Lung Cancer Biomarker Center A. SPECIFIC AIMS 1. To develop and prospectively follow a large cohort at high-risk for lung cancer. Individuals are recruited to one of two different ... Rom, William
Nashville Early Diagnosis Lung Cancer Project Massion, Pierre
National Ovarian Cancer Early Detection Program Blood and Genetics Fishman, David
New Biomarkers & Dysplastic Respiratory Epithelium Not listed
Novel Surveillance Strategies For Hereditary Nonpolyposis Colon Cancer Family Members Lynch, Henry
Novel approaches to study immune responses to post translational modifications for cancer detection We propose to develop a BDL to discover immune-based biomarkers for the detection of breast cancers, based on fundamental tumor-specific changes in protein ... LaBaer, Joshua
Ornithine decarboxylase (ODC) Polymorphism and Breast and Prostate Cancer Helzlsouer, Kathy
Ovarian Cancer Screening Pilot Trial In High Risk Women BACKGROUND: No proven ovarian cancer (OC) screening strategy exists for women who are at increased risk for the disease. A risk of ovarian cancer algorithm ... Lynch, Henry
PASS Reference Set Application: Carroll Univ. of California SF (2012) PC101769 Predicting Prostate Cancer Progression at Time of Diagnosis Carroll, Peter R.
Announcement 03/14/2018
Thank you to everyone to made the 10th EDRN Scientific Workshop a success. The next event is the 33rd EDRN Steering Committee Meeting from September 5-6, 2018 in Boston, MA. Details will be available soon.

Three new FOAs on the Human Tumor Atlas and associated with the Cancer Moonshot Initiative have been released. Please click here for more information.

Announcement 10/23/2017

Three new FOAs on the Human Tumor Atlas and associated with the Cancer Moonshot Initiative have been released. Please click here for more information.

EDRN Founder Honored

Dr. Sudhir Srivastava was honored with the Distinguished Service Award from the American Pancreatic Association at the group's annual meeting this year, for his outstanding commitment to pancreatology.