Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Protocols / Seattle Area Hormone and Reproductive Epidemiology Breast Cancer Study
Not an EDRN Protocol

Seattle Area Hormone and Reproductive Epidemiology Breast Cancer Study

1035

No involved investigator sites defined.

The SHARE Study (Seattle Area Hormone And Reproductive Epidemiology Breast Cancer Study) is a five-year, population-based case-control study, funded by the National Institutes of Health, to investigate the relationship between hormone replacement therapy (HRT) and invasive lobular and invasive ductal breast cancer among women 55 to 74-years of age. The case group of 1043 women consists of 271 invasive lobular, 330 invasive ductal and lobular, and 442 invasive ductal, breast cancer cases. The control group consists of 469 controls drawn from the general population. The specific study hypotheses that were tested: 1. Is the use of combined estrogen-progestin hormone replacement therapy (CHRT) associated with an increase in the incidence of invasive lobular breast cancer in women aged 55-74a 2. Is the use of CHRT associated with an increase in the incidence of invasive ductal breast cancer in women aged 55-74a 3. Does the duration, patterns and/or recency of CHRT use influence the size of the associationa 4. Is the use of CHRT associated with particular tumor marker profiles or characteristics of lobular and ductal breast cancers

There are currently no biomarkers annotated for this protocol.

No datasets are currently associated with this protocol.


News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement