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Novel approaches to study immune responses to post translational modifications for cancer detection

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LaBaer, JoshuaArizona State University

No coordinating investigator defined.

Proteomics
Breast and Gynecologic Cancers Research
1

We propose to develop a BDL to discover immune-based biomarkers for the detection of breast cancers, based on fundamental tumor-specific changes in protein glycosylation.

Aim 1. Development a multiplexed platform to produce O-glycosylated proteins Aim 2. Proteome scale glycoprotein array development and production Aim 3. Identification of anti-glycoprotein antibody (TAAb-AGP) biomarkers in breast cancer
Protein array and ELISA

There are currently no biomarkers annotated for this protocol.

No datasets are currently associated with this protocol.


Announcement 01/27/2020

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