You are here: Home / Protocols / PCA3 Reference Set Application: Samantha Maragh NIST
Team Project

PCA3 Reference Set Application: Samantha Maragh NIST


No coordinating investigator defined.

Prostate and Urologic Cancers Research Group

This requested sample cohort is intended to evaluate the potential for two mitochondrial DNA (mtDNA) biomarkers to be used for non-invasive early detection of prostate cancer. Among men with elevated PSA, our previous study indicated these mtDNA biomarkers may have value to segregate men with prostate cancer from men without prostate cancer when these markers were measured in bio-banked urine specimens. In that study since PSA was elevated among cancers and controls it was therefore not specific enough to infer disease state. Prostate cancer individuals in that study were primarily Gleason 6 (3+3), suggesting these biomarkers may have utility for early detection. We concluded from that investigation that a follow up confirmation study with increased sample size appropriately powered with the potential for combination of mtDNA biomarker results with other prostate cancer biomarkers is of value to corroborate and extend those findings.

There are currently no biomarkers annotated for this protocol.

No datasets are currently associated with this protocol.

🔜 Data-Sci Workshop
The EDRN Biomarker Data Science Workshop is coming this August, 2020. More details available soon.
Announcement 03/17/2020

The EDRN Registration page will be available soon to register for the 35th EDRN Steering Committee Meeting, now scheduled to take place from June 30-July 2, 2020, in Tempe, AZ.

This icon signifies that something is happening and we kindly ask you to please wait