8:00 a.m. – 8:05 a.m.

General Announcements

8:05 a.m – 8:10 a.m.

01: Welcome and Opening of 2023 EDRN Scientific Workshop

• (In-person) Sudhir Srivastava, PhD, MPH, National Cancer Institute
• (In-person) Arul Chinnaiyan, MD, University of Michigan Medical School
• (In-person) Karen Anderson, MD, PhD, Arizona State University/The Biodesign Institute

8:10 a.m. – 8:15 a.m.

02: Opening Remarks

(In-person) Lori Minasian, MD, FACP, Deputy Director, Division of Cancer Prevention National Cancer Institute

8:15 a.m. – 8:45 a.m.

03: Keynote Address: Development of ERG gene fusions as a biomarker for prostate cancer: An EDRN journey

(In-person) Arul Chinnaiyan, MD, University of Michigan Medical School

8:45 a.m. – 8:50 a.m.

Q&A

8:50 a.m – 11:50 a.m.

Session 1: Advances in Cancer Diagnostics with a Focus on Multi Cancer Early Detection

8:50 a.m. – 8:55 a.m.

04: Introduction to the Session

(In-person) Samir Hanash, MD, PhD, The University of Texas MD Anderson Cancer Center

8:55 a.m. – 9:15 a.m.

05: Fragmentomics-based MCEDs, BestSeqS and its upcoming validation (VALETE)

(In-person) Cristian Tomasetti, MD, City of Hope/TGen

9:15 a.m. – 9:20 a.m

Q&A

9:20 a.m. – 9:40 a.m.

06: MCED - Innovation for Population Health

(In-person) Josh Ofman, MD, MS, GRAIL

9:40 a.m. – 9:45 a.m.

Q&A

9:45 a.m. – 10:05 a.m.

Break

10:05 a.m. – 10:25 a.m.

07: Shifting the Paradigm in Cancer Screening: Multi-cancer Early Detection Testing

(In-person) Tomasz Beer, MD, Exact Sciences

10:25 a.m. – 10:30 a.m.

Q&A

10:30 a.m. – 10:50 a.m.

08: Somatic clonal evolution across the human lifetime: a complicating factor for early cancer detection but opportunity for screening risk stratification

(In-person) Jesse Salk, MD, PhD, TwinStrand Biosciences, University of Washington, Fred Hutchinson Cancer Center

10:50 a.m. – 10:55 a.m.

Q&A

10:55 a.m. – 11:15 a.m.

09: Cancer Screening Research Network and the Vanguard Pilot Study
(In-person) Lori Minasian, MD, FACP, Deputy Director, Division of Cancer Prevention, National Cancer Institute

11:15 a.m. – 11:20 a.m.

Q&A

11:20 a.m. – 11:50 a.m.

Panel Discussion

Moderator: Samir Hanash, MD, PhD, The University of Texas MD Anderson Cancer Center

Panelists:

• (In-person) Samir Hanash, MD, PhD, The University of Texas MD Anderson Cancer Center
• (In-person) William Bulman MD, Veracyte
• (In-person) Cristian Tomasetti, MD, City of Hope/TGen
• (In-person) Josh Ofman, MD, MS, GRAIL
• (In-person) Zack Foda, MD, PhD, Johns Hopkins University
• (In-person) Jesse Salk, MD, PhD, TwinStrand Biosciences, University of Washington, Fred Hutchinson Cancer Center
• (In-person) Lori Minasian, MD, FACP, National Cancer Institute
• (In-person) Merel Grey, Esq., National Alliance of State Prostate Cancer Coalitions

11:50 a.m. – 1:30 p.m.

Lunch (On Your Own)

11:50 a.m. – 1:30 p.m.

EDRN Executive Committee Meeting (Closed Session)

1:30 p.m. – 4:00 p.m.

Session 2: Application of Big Data and Artificial Intelligence Early Cancer Detection

1:30 p.m. – 1:40 p.m.

10: Introduction to the Session

Moderator: (In-person) Cecilia Yeung, MD, Fred Hutchinson Cancer Center

1:40 p.m. – 2:10 p.m.

11: Keynote Address: Stress-testing and improving early cancer detection via the PCS framework

(In-person) Bin Yu, PhD, University of California, Berkeley

2:10 p.m. – 2:15 p.m.

Q&A

2:15 p.m. – 2:35 p.m.

12: Advancing Robust Imaging AI for Early Lung Cancer Detection

(In-person) William Hsu, PhD, The University of California, Los Angeles

2:35 p.m. – 2:40 p.m.

Q&A

2:40 p.m. – 3:00 p.m.

13: The Moffitt CVC: A pan-cancer quantitative imaging Clinical Validation Center

(In-person) Matt Schabath, PhD, H. Lee Moffitt Cancer and Research Institute, Inc.

3:00 p.m. – 3:05 p.m.

Q&A

3:05 p.m. – 3:25 p.m.

14: AI for Personalized Cancer Screening

(In-person) Adam Yala, PhD, University of California, Berkeley

3:25 p.m. – 3:30 p.m.

Q&A

3:30 p.m. – 3:50 p.m.

15: Machine Learning Innovations and the Percepta Nasal Swab Classifier for Indeterminate Lung Nodules

(In-person) William Bulman MD, Veracyte

3:50 p.m. – 3:55 p.m.

Q&A

3:55 p.m. – 4:15 p.m.

Break

4:15 p.m. – 4:35 p.m.

16: Special Presentation by ARPA-H Program Manager

(Virtual) Ross Uhrich, DMD, MBA, Advanced Research Projects Agency for Health

4:35 p.m. – 4:40 p.m.

Q&A

4:40 p.m. – 5:00 p.m.

17: Blood-based Biomarkers for Personalized Risk Assessment of Pancreatic Cancer

(In-person) Johannes Fahrmann, PhD, The University of Texas MD Anderson Cancer Center

5:00 p.m. – 5:05 p.m.

Q&A

5:05 p.m. – 5:55 p.m.

Session 3: Poster Lightening Presentations (10 minutes each)

Moderator: (In-person) Karen Anderson, MD, PhD, Arizona State University/The Biodesign Institute

5:05 p.m. – 5:13 p.m.

18: Presentation 1: Early Stage Investigator: Urinary Marker Panels for Aggressive Prostate Cancer Detection

(Virtual) Mamie Lih, PhD, Johns Hopkins University

5:13 p.m. – 5:15 p.m.

Q&A

5:15 p.m. – 5:23 p.m.

19: Presentation 2: A Cell-Acquiring Fallopian Tube Endoscope

(In-person) Ie-Ming Shih, MD, PhD, Johns Hopkins Medical Institutions for Jennifer Barton, MD, PhD, University of Arizona

5:23 p.m. – 5:25 p.m..

Q&A

5:25 p.m. – 5:33 p.m.

20: Presentation 3: Multicolor DNA-Gold Nanoprobes-based Multiplex Biosensing Technology for Ultrasensitive Quantification of Serum miRNAs and Advancing the Pancreatic Cancer Diagnosis

(Virtual) Prakash Kshirsagar, PhD, University of Nebraska Medical Center

5:33 p.m. – 5:35 p.m.

Q&A

5:35 p.m. – 5:43 p.m.

21: Presentation 4: Study Design and Preliminary Findings from the Throat and Other HPV-related Cancers in Men: Identifying Them Early (TRINITY) Study

(Virtual) Kristina Dahlstrom, PhD, Baylor College of Medicine

5:43 p.m. – 5:45 p.m.

Q&A

5:45 p.m. – 5:53 p.m.

22: Presentation 5: Application of Multi-Cancer Early Detection to Lung and Breast Cancer Screening Populations

(In-person) Jennifer Dennison, PhD, The University of Texas MD Anderson

5:53 p.m. – 5:55 p.m.

Q&A

7:00 p.m. - 9:00 p.m.

Poster Session