A Blood-Based Assay for Detection of Patients with Advanced Adenomas.
Abstract
Blood-based screening for colorectal cancer could improve testing uptake and outcomes. We propose novel methods to detect AAs in plasma using cfDNA fragmentation patterns, cancer-associated proteins, and aneuploidy with high specificity. Larger studies are needed to validate clinical utility.
EDRN PI Authors
- (None specified)
Medline Author List
- Ansari SK
- Cohen JD
- Diergaarde B
- Dobbyn L
- Douville C
- Gibbs P
- Grant H
- Kinzler KW
- Kuo A
- Lahouel K
- Nehme N
- O'Broin-Lennon AM
- Papadopoulos N
- Popoli M
- Ptak J
- Schoen RE
- Silliman N
- Tie J
- Tomasetti C
- Vogelstein B
- Wang Y