The Germline and Somatic Origins of Prostate Cancer Heterogeneity.
Abstract
This study uncovered 223 recurrently mutated driver regions using the largest cohort of prostate tumors to date. It reveals associations between germline SNPs, somatic drivers, and tumor aggression, offering significant insights into how prostate tumor evolution is shaped by germline factors and the timing of somatic mutations.
EDRN PI Authors
Medline Author List
- Bell C
- Bergeron A
- Bhandari V
- Bornman RMS
- Boutros PC
- Bristow RG
- Chan EKF
- Chow K
- Clarkson MJ
- Cmero M
- Corcoran NM
- Costello AJ
- Espiritu SMG
- Foucal A
- Fox NS
- Fradet Y
- Fraser M
- Freedman ML
- Georgeson P
- Gusev A
- Hayes VM
- He HH
- Heisler LE
- Houlahan KE
- Hovens CM
- Hovington H
- Huang V
- Hung RJ
- Jaratlerdsiri W
- Jiang J
- Jovelin R
- Jung CH
- Kerger M
- Kishan AU
- Kurganovs N
- Lacombe L
- Lalansingh CM
- Lesurf R
- Liu LY
- Livingstone J
- Lolkema MP
- Lonie A
- Mangiola S
- Mani RS
- McCoy PJ
- McPherson JD
- Mcintosh L
- Mutambirwa SBA
- Nguyen A
- O'Connor E
- Orain M
- Papenfuss AT
- Park DJ
- Pasaniuc B
- Peters JS
- Picard V
- Pomerantz MM
- Pope BJ
- Prokopec SD
- Ramanand SG
- Reimand J
- Ryan A
- Sabelnykova V
- Salcedo A
- Schwarz T
- Sendorek DHS
- Seo JH
- Shiah YJ
- Sietsma Penington J
- Stricker PD
- Stuchbery R
- Taraszka K
- Têtu B
- Wakefield M
- Waszak SM
- Weischenfeldt J
- Yamaguchi TN
- Yuan J
- Zaitlen N
- Zhu H
- van Riet J
- van der Kwast T