Liver Cancer Reference Set Application (Rapid): Chilkoti (2019)
- Abbreviated Name
- Liver CA Ref Set App (Rapid): Chilkoti (2019)
- Lead Investigator
- Chilkoti, Ashutosh — Duke University
- Coordinating Investigator
- Feng, Ziding — Fred Hutchinson Cancer Center
- Involved Investigators
Abstact
See objectives
Aims
See Objectives
Analytic Method
We will analyze 100 samples from the reference set (50 early stage HCC cases and 50 at risk of HCC with liver disease (cirrhotic). Samples will be analyzed in parallel on 6-plex D4 POCT chips and standard ELISA kits to directly compare the analytical performance between the two. All test points will be run in triplicate. The assay will be evaluated in terms of the following “figures-of-merit” (FOM): limit-of-blank (LOB), limit-of-detection (LOD; synonymous with ‘analytical sensitivity’), linear calibration range (LCR), upper and lower limits of quantification (LOQ) and coefficient-of-variance (COV).
Biomarkers
Data Collections
- No data available at this time for this protocol
Team Project
- Protocol ID
- 457
- Protocol Type
- Reference Set
- Field of Research
- Proteomics
- Collaborative Group
- G.I. and Other Associated Cancers Research Group
- Cancer Types
-
- Liver cell carcinoma
- Phased Status
- 1