Liver Cancer Reference Set Application (Rapid): Chilkoti (2019)

Abbreviated Name
Liver CA Ref Set App (Rapid): Chilkoti (2019)
Lead Investigator
Chilkoti, AshutoshDuke University
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators

Abstact

See objectives

Aims

See Objectives

Analytic Method

We will analyze 100 samples from the reference set (50 early stage HCC cases and 50 at risk of HCC with liver disease (cirrhotic). Samples will be analyzed in parallel on 6-plex D4 POCT chips and standard ELISA kits to directly compare the analytical performance between the two. All test points will be run in triplicate. The assay will be evaluated in terms of the following “figures-of-merit” (FOM): limit-of-blank (LOB), limit-of-detection (LOD; synonymous with ‘analytical sensitivity’), linear calibration range (LCR), upper and lower limits of quantification (LOQ) and coefficient-of-variance (COV).

Biomarkers

Data Collections

  • No data available at this time for this protocol
 Team Project
Protocol ID
457
Protocol Type
Reference Set
Field of Research
Proteomics
Collaborative Group
G.I. and Other Associated Cancers Research Group
Cancer Types
  • Liver cell carcinoma
Phased Status
1

Associated Forms