Germline Genetic Variants and Faliure of Acitve Sureveillance

Abbreviated Name
PASS Ref Set App: Catalona - Germline Variants
Lead Investigator
Lin UW, Daniel W.University of Washington
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators



Specific Aim 1: Designing custom content array and genotyping We will work closely with all collaborators and CIDR to incorporate the 10,000 custom content variants specific to PC on the Illumina Infinium Multi-Ethnic Array. All 5061 DNA samples from men with PC on AS will be sent to CIDR for genotyping. Specific Aim 2: Testing previously reported variants Here, we will test the association between AS and variants previously associated with PC susceptibility or aggressiveness from the literature, study collaborators, and other colleagues. Specific Aim 3: Evaluating associations with new variants In this aim we will test the associations between the genome-wide variants and AS.

Analytic Method


  • No biomarkers available at this time for this protocol

Data Collections

  • No data available at this time for this protocol
 Team Project
Protocol ID
Protocol Type
Field of Research
Collaborative Group
Prostate and Urologic Cancers Research Group
Cancer Types
  • Malignant neoplasm of prostate
Phased Status

Associated Forms