Germline Genetic Variants and Faliure of Acitve Sureveillance

Abbreviated Name
PASS Ref Set App: Catalona - Germline Variants
Lead Investigator
Lin UW, Daniel W.University of Washington
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators

Abstract

No abstract availalbe.

Aims

Specific Aim 1: Designing custom content array and genotyping We will work closely with all collaborators and CIDR to incorporate the 10,000 custom content variants specific to PC on the Illumina Infinium Multi-Ethnic Array. All 5061 DNA samples from men with PC on AS will be sent to CIDR for genotyping. Specific Aim 2: Testing previously reported variants Here, we will test the association between AS and variants previously associated with PC susceptibility or aggressiveness from the literature, study collaborators, and other colleagues. Specific Aim 3: Evaluating associations with new variants In this aim we will test the associations between the genome-wide variants and AS.

Analytic Method

No analytic method available.

Publications

  • No publications available at this time for this protocol.

Biomarkers

  • No biomarkers available at this time for this protocol.

Data Collections

  • No data collections available at this time for this protocol.
 Team Project
Start Date
Feb 26 2018
Finish Date
Dec 31 2021
Protocol ID
433
Protocol Type
Single
Fields of Research
  • Genomics
Collaborative Group
Prostate and Urologic Cancers Research Group
Cancer Types
  • Malignant neoplasm of prostate
Phased Status
2

Associated Forms