Ovarian Cancer Detection by Uterine Lavage DNA and Serum Proteins: A Phase 2 Biomarker Study

Uterine Lavage

This project investigates the complementarity of tumor DNA (tDNA) in uterine lavage to serum proteins for detection of ovarian cancer and builds on the results from project 1. Since there is no biobank of uterine lavage a prospective study is required. Two hundred patients scheduled for surgery for suspected ovarian cancer will be enrolled at four recruitment sites (50 pts at each site) and blood drawn before anesthesia and uterine lavage obtained before surgery. tDNA will be analyzed at two sequencing sites and serum proteins measured at two immunoassay sites.

No datasets are currently associated with this protocol.

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