Lung Reference Set A Application: Pierre Massion-Vanderbilt (2017)

Abbreviated Name
Lung Ref Set A App: Massion (2017)
Lead Investigator
Grogan, EricVanderbilt -Ingram Cancer Center
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators

Abstract

No abstract availalbe.

Aims

No aims available.

Analytic Method

No analytic method available.

Outcome

The CBSI measurement of CYFRA 21-1 is not observed to have discriminatory ability between lung cancer cases and high-risk controls in the dataset sampled from the EDRN Lung Reference Set A. Pre-specied analyses: -sensitivity at 80% specicity: 0:27 (95% CI 0:18; 0:37) - specicity at 80% sensitivity: 0:25 (95% CI 0:16; 0:4). Both observed values are only somewhat greater than 20% (the expected value assuming no discrimination) and 95% condence intervals do not exclude the null. The corresponding positive and negative diagnostic likelihood ratios and the overall AUC similarly do not suggest much discrimination.

Publications

  • No publications available at this time for this protocol.

Biomarkers

Data Collections

  • No data collections available at this time for this protocol.
 Team Project
Start Date
Jun 13 2017
Estimated Finish Date
Oct 13 2017
Finish Date
Jan 2 2018
Protocol ID
422
Protocol Type
Reference Set
Fields of Research
  • UNKNOWN
Collaborative Group
Lung and Upper Aerodigestive Cancers Research Group
Cancer Types
  • Malignant neoplasm of bronchus and lung
Phased Status
1

Associated Forms