Breast Reference Set Application: Chris Li-FHCRC (2015)
- Abbreviated Name
- Breast Ref Set App: Li (2015)
- Lead Investigator
- Li, Christopher — Fred Hutchinson Cancer Center
- Coordinating Investigator
- Feng, Ziding — Fred Hutchinson Cancer Center
- Involved Investigators
Abstract
See objectives
Aims
No aims available.
Analytic Method
We propose to use our existing arrays for biomarker evaluation but to focus the evaluation on 9 candidates: KLK5,CRHBP, TFRC, ITGB4, RASGRF2, MUC5AC, FOLR3, YWHAB, CNOT7. These include the 8 marker panel described above that achieved 35% sensitivity at 5% specificity and the one additional marker from our A list that validated in our independent preclinical OS-WHI samples, CRHBP. The primary data analysis will focus on the combination of these 9 markers derived by logistic regression from the OS-WHI samples.
Outcome
See objectives
Publications
- No publications available at this time for this protocol.
Biomarkers
Data Collections
- No data collections available at this time for this protocol.
Team Project
- Start Date
- Apr 12 2015
- Estimated Finish Date
- Oct 12 2015
- Finish Date
- Apr 15 2015
- Protocol ID
- 403
- Protocol Type
- Reference Set
- Fields of Research
-
- Proteomics
- Collaborative Group
- Breast and Gynecologic Cancers Research Group
- Cancer Types
-
- Malignant neoplasm of breast