Breast Reference Set Application: Chris Li-FHCRC (2015)

Abbreviated Name
Breast Ref Set App: Li (2015)
Lead Investigator
Li, ChristopherFred Hutchinson Cancer Center
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators

Abstact

See objectives

Aims

No aims available.

Analytic Method

We propose to use our existing arrays for biomarker evaluation but to focus the evaluation on 9 candidates: KLK5,CRHBP, TFRC, ITGB4, RASGRF2, MUC5AC, FOLR3, YWHAB, CNOT7. These include the 8 marker panel described above that achieved 35% sensitivity at 5% specificity and the one additional marker from our A list that validated in our independent preclinical OS-WHI samples, CRHBP. The primary data analysis will focus on the combination of these 9 markers derived by logistic regression from the OS-WHI samples.

Publications

  • No publications available at this time for this protocol.

Biomarkers

Data Collections

  • No data collections available at this time for this protocol.
 Team Project
Start Date
Apr 12 2015
Estimated Finish Date
Oct 12 2015
Finish Date
Apr 15 2015
Protocol ID
403
Protocol Type
Reference Set
Field of Research
Proteomics
Collaborative Group
Breast and Gynecologic Cancers Research Group
Cancer Types
  • Malignant neoplasm of breast

Associated Forms