Breast Reference Set Application: Karen Abbott- University of Arkansas (2013)

Abbreviated Name
Breast Ref Set App: Abbott (2013)
Lead Investigator
Abbott, KarenFlorida International University
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators

Abstact

Aims

Validating B 1,6 as a biomarker for the early detection of breast cancer. Then continuing to validate L-PHA with the use of Breast Reference Set 2 samples.

Analytic Method

The analysis for LPHA-periostin will be similar. In each case, data will be fit to the fixed-effects linear model yij = u + ai + Bj+ eij, wehre yij is the level, u is the grand mean, ai represent the pairing effect (age-matching), bj the tumor/normal effect,and eij random variation. Transformations of the response levels will be analyzed with the method of Box and Cox (1964); based on the preliminary data we anticipate the log transformation will be adequate. Basic plots of the transformed data will be analyzed for skewness and outliers.

Biomarkers

Data Collections

  • No data available at this time for this protocol
Protocol ID
378
Protocol Type
Reference Set
Field of Research
Glycomics
Collaborative Group
Breast and Gynecologic Cancers Research Group
Cancer Types
  • Malignant neoplasm of breast

Associated Forms