Methylation & Proteomics-Based Detection of Bladder Cancer

Abbreviated Name
BLADDER-PRE-VAL
Lead Investigator
Cairns, PaulFox Chase Cancer Center
Coordinating Investigator
Feng, Ziding Fred Hutchinson Cancer Center
Involved Investigators

Abstact

Study never Launched

Aims

This study will test the sensitivity of gene methylation in the presence of clinically evident, pathologically confirmed bladder cancer. This study will test the specificity of gene methylation in two groups of participants without bladder cancer - requiring cystoscopy for hematuria and for foreign body (urinary stones, stents, and catheters) or infection.

Analytic Method

Quantitative real time methylation specific PCR (qMSP) of urine sediment DNA using a panel of several methylated gene markers.

Publications

  • No publications available at this time for this protocol.

Biomarkers

  • No biomarkers available at this time for this protocol.

Data Collections

  • No data collections available at this time for this protocol.
Start Date
Feb 1 2008
Estimated Finish Date
Feb 1 2009
Finish Date
May 1 2010
Protocol ID
226
Protocol Type
Collaboration
Field of Research
Hypermethylation
Collaborative Group
Prostate and Urologic Cancers Research Group
Cancer Types
  • Malignant neoplasm of bladder
Phased Status
1

Associated Forms