Standard Specimen Reference Set: Liver
- Abbreviated Name
- LIVER REF
- Lead Investigator
- Parikh, Neehar — University of Michigan
- Coordinating Investigator
- Feng, Ziding — Fred Hutchinson Cancer Center
- Involved Investigators
-
- Feng, Ziding — Fred Hutchinson Cancer Center
- Schwartz, Myron — Mount Sinai Hospital
- Befeler, Alex — Saint Louis University
- Roberts, Lewis — Mayo Clinic
- Nguyen, Mindie — Stanford University
- Parikh, Neehar — University of Michigan
- Srivastava, Sudhir — National Cancer Institute
- Reddy, Rajender — University of Pennsylvania
Abstact
Utilize the remaining specimens collected under the DCP protocol to develop and validate markers for the early detection of HCC
Aims
Specific Aims Aim 1: To determine the sensitivity and specificity of des-gamma carboxyprothrombin (DCP) for the diagnosis of early hepatocellular carcinoma (HCC). Aim 2: To compare the accuracy of DCP and Alpha-fetoprotein (AFP) for the diagnosis of early HCC. Aim 3: To determine whether demographic or etiology of underlying liver disease alter the expression of DCP or AFP.
Analytic Method
N/A
Biomarkers
- No biomarkers available at this time for this protocol
Data Collections
- No data available at this time for this protocol
Team Project
- Protocol ID
- 134
- Protocol Type
- Reference Set
- Field of Research
- Other, Specify
- Collaborative Group
- G.I. and Other Associated Cancers Research Group
- Cancer Types
-
- Liver cell carcinoma