Abbreviated Name

LIVER REF

Lead Investigator

Parikh, Neehar — University of Michigan

Coordinating Investigator

Feng, Ziding — Fred Hutchinson Cancer Center

Involved Investigators

• Feng, Ziding — Fred Hutchinson Cancer Center
• Schwartz, Myron — Mount Sinai Hospital
• Befeler, Alex — Saint Louis University
• Roberts, Lewis — Mayo Clinic
• Nguyen, Mindie — Stanford University
• Parikh, Neehar — University of Michigan
• Srivastava, Sudhir — National Cancer Institute
• Reddy, Rajender — University of Pennsylvania

Abstact

Utilize the remaining specimens collected under the DCP protocol to develop and validate markers for the early detection of HCC

Aims

Specific Aims Aim 1: To determine the sensitivity and specificity of des-gamma carboxyprothrombin (DCP) for the diagnosis of early hepatocellular carcinoma (HCC). Aim 2: To compare the accuracy of DCP and Alpha-fetoprotein (AFP) for the diagnosis of early HCC. Aim 3: To determine whether demographic or etiology of underlying liver disease alter the expression of DCP or AFP.

Analytic Method

N/A

Biomarkers

• No biomarkers available at this time for this protocol

Data Collections

• No data available at this time for this protocol

 Team Project

Protocol ID

134

Protocol Type

Reference Set

Field of Research

Other, Specify

Collaborative Group

G.I. and Other Associated Cancers Research Group

Cancer Types

• Liver cell carcinoma