Abbreviated Name

GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett’s Esophagus Progression to Dysp

Lead Investigator

Brenner, Dean — University of Michigan

Coordinating Investigator

No coordinating investigator

Involved Investigators

• Brenner, Dean — University of Michigan
• Costa, Jose — Yale University School of Medicine
• Chia (Retired), David — University of California Los Angeles

Abstact

Aims

Establish the feasibility of measuring the biomarkers in a multi-center clinical trial. 1.2   Estimate the variance of the biomarkers in cohorts defined by sex, race, age and histologic diagnosis (Barrett's intestinal metaplasia, Barrett's intestinal dysplasia [low-grade or high-grade], Adenocarcinoma, and non-Barrett’s controls). 1.3   Determine if the distributions of the biomarkers differ significantly among patients with different histologic diagnoses.

Analytic Method

Biomarkers

• No biomarkers available at this time for this protocol

Data Collections

• No data available at this time for this protocol

Protocol ID

107

Field of Research

Glycomics

Collaborative Group

G.I. and Other Associated Cancers Research Group

Cancer Types

• Malignant neoplasm of esophagus