ZFP36L1
- Aliases
-
- BERG36
- BRF1
- Berg36
- Butyrate response factor 1
- EGF-response factor 1
- ERF-1
- ERF1
- Protein TIS11B
- RNF162B
- TIS11B
- ZFP36L1
- butyrate response factor 1
- cMG1
- early response factor Berg36
- zinc finger protein 36, C3H type-like 1
- zinc finger protein 36, C3H1 type-like 1
- zinc finger protein, C3H type, 36-like 1
- Description
- ZFP36L1 is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The ZFP36L1 gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. ZFP36L1 contains a putative zinc finger domain with a repeating cys-his motif. ZFP36L1 is believed to be a nuclear transcription factor most likely functioning in regulating the response to growth factors. Different isoforms encoded by alternatively spliced transcript variants have been isolated.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- ZFP36L1
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.