NOS1
- Aliases
-
- Constitutive NOS
- EC 1.14.13.39
- IHPS1
- N-NOS
- NC-NOS
- NOS
- NOS type I
- NOS1
- Neuronal NOS
- Peptidyl-cysteine S-nitrosylase NOS1
- bNOS
- constitutive NOS
- nNOS
- neuronal NOS
- nitric oxide synthase 1 (neuronal)
- nitric oxide synthase, brain
- peptidyl-cysteine S-nitrosylase NOS1
- Description
- NOS1, or nitric oxide synthase 1 (neuronal), along with inducible nitric oxide synthase (NOS2) and endothelial nitric oxide synthase (NOS3), catalyze the generation of nitric oxide and L-citrulline from L-arginine and molecular oxygen. Nitric oxide is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter. NOS1 also displays antimicrobial and antitumoral activities.
Attributes
- QA State
- Curated
- Type
- Protein
- HGNC Name
- NOS1
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.