MCAM

Aliases
  • CD146
  • CD146 antigen
  • Cell surface glycoprotein P1H12
  • Gicerin
  • MCAM
  • MUC18
  • Melanoma cell adhesion molecule
  • Melanoma-associated antigen A32
  • Melanoma-associated antigen MUC18
  • S-endo 1 endothelial-associated antigen
  • cell surface glycoprotein MUC18
  • cell surface glycoprotein P1H12
  • melanoma adhesion molecule
  • melanoma cell adhesion molecule
  • melanoma-associated antigen A32
  • melanoma-associated antigen MUC18
Description
From UniProtKB/Swiss-Prot: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Attributes
QA State
Curated
Type
Glycomic
HGNC Name
MCAM
Certifications
  • None
QA State for Head and Neck
Curated

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

Certifications
  • None
QA State for Liver
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

Certifications
  • None
QA State for Prostate
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.