Aliases

• BP-4
• HT29-IGFBP
• IBP4
• IGF-binding protein 4
• IGFBP-4
• IGFBP4
• insulin-like growth factor binding protein 4

Description

The IGFBP4 gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP4 binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

Attributes

QA State

Under Review

Type

Protein

HGNC Name

IGFBP4