GFPT1

Aliases:
This biomarker is also known as:
  • Hexosephosphate aminotransferase 1
  • GFPT1
  • GFPT
  • glutamine--fructose-6-phosphate transaminase 1
  • GFAT
  • Glutamine:fructose 6 phosphate amidotransferase 1
  • GFAT1m
  • Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
  • GFA
  • D-fructose-6-phosphate amidotransferase 1
  • GFAT1
  • GFAT 1

Description…

GFPT1 is the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. It appears to catalyze the formation of glucosamine 6-phosphate. It may also be involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. GFPT1 is predominantly expressed in skeletal muscle, selectively expressed in striated muscle, and not expressed in brain.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: GFPT1

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access to this biomarker.

Version 5.1.0