CSNK1E
- Aliases
-
- CKI-epsilon
- CKIE
- CKIe
- CKIepsilon
- CSNK1E
- EC 2.7.11
- EC 2.7.11.1
- HCKIE
- casein kinase 1, epsilon
- casein kinase I isoform epsilon
- Description
- CSNK1E is a serine/threonine protein kinase and a member of the casein kinase I protein family. Casein kinases are characterized by their preferential utilization of acidic proteins such as caseins as substrates. Members of the casein kinase I protein family have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, and have been shown to phosphorylate a variety of proteins, including itself. CSNK1E is a monomeric cytoplasmic protein. CSNK1E has been shown to phosphorylate period, a circadian rhythm protein, and as such is a central component of the circadian clock. CSNK1E may act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Two transcript variants encoding the same protein have been found for this gene.
Attributes
- QA State
- Under Review
- Type
- Protein
- HGNC Name
- CSNK1E
- Certifications
-
- None
- QA State for Breast
- Under Review
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.
Non-Public Biomarker
Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.