CDKN2C

Aliases
  • CDK6 inhibitor p18
  • CDKN2C
  • CDKN6
  • Cyclin-dependent kinase 6 inhibitor
  • INK4C
  • cyclin-dependent inhibitor
  • cyclin-dependent kinase 4 inhibitor C
  • cyclin-dependent kinase 6 inhibitor p18
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • p18
  • p18-INK4C
  • p18-INK4c
  • p18-INK6
Description
From NCBI Gene: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
Attributes
QA State
Under Review
Type
Gene
HGNC Name
CDKN2C
Certifications
  • None
QA State for Prostate
Under Review

 Non-Public Biomarker

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 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.