ANGPTL3

Aliases
  • ANG-5
  • ANGPT5
  • ANGPTL3
  • Angiopoietin-5
  • Angiopoietin-like protein 3
  • FHBL2
  • angiopoietin 5
  • angiopoietin-like 3
  • angiopoietin-related protein 3
Description
ANGPTL3, or angiopoietin-like 3, is a member of the angiopoietin-like family of secreted factors. It is a secreted protein expressed primarily in the liver, and also weakly expressed in the kidney. ANGPTL3 has the characteristic angiopoietin structure, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. ANGPTL3 is also thought to be involved in the regulation of angiogenesis.
Attributes
QA State
Under Review
Type
Protein
HGNC Name
ANGPTL3
Certifications
  • None
QA State for Lung
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

Certifications
  • None
QA State for Pancreas
Under Review

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.

 Non-Public Biomarker

Organ-specific information for this biomarker is currently being annotated or is "under review". Logging in may give you privileges to view additional information. Contact the Informatics Center if you believe you should have access.