Early Detection Research Network

YWHAE

Aliases:
This biomarker is also known as:
  • 14-3-3E,
  • MDCR,
  • MDS,
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide,
  • protein kinase C inhibitor protein-1,
  • mitochondrial import stimulation factor L subunit,
  • KCIP-1,
  • 14-3-3 protein epsilon,
  • tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide,
  • 14-3-3 epsilon,
  • FLJ45465,
  • YWHAE,

Description…

From NCBI Gene: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Gene
HGNC Name: YWHAE

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2