Early Detection Research Network

TSPAN6

Aliases:
This biomarker is also known as:
  • Tspan-6,
  • TSPAN-6,
  • Tetraspanin TM4-D,
  • TM4SF6,
  • Putative NF-kappa-B-activating protein 321,
  • tetraspanin TM4-D,
  • tetraspan TM4SF,
  • tetraspanin-6,
  • T245 protein,
  • TSPAN6,
  • putative NF-kappa-B-activating protein 321,
  • T245,
  • tetraspanin 6,
  • Transmembrane 4 superfamily member 6,
  • transmembrane 4 superfamily member 6,
  • A15 homolog,

Description…

From NCBI Gene: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: TSPAN6

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2