Early Detection Research Network

TRAF3IP2

Aliases:
This biomarker is also known as:
  • ACT1,
  • connection to IKK and SAPK/JNK,
  • C6orf5,
  • NFkB-activating protein ACT1,
  • TRAF3IP2,
  • Nuclear factor NF-kappa-B activator 1,
  • chromosome 6 open reading frame 5,
  • adapter protein CIKS,
  • CIKS,
  • Connection to IKK and SAPK/JNK,
  • TRAF3 interacting protein 2,
  • nuclear factor NF-kappa-B activator 1,
  • C6orf2,
  • TRAF3-interacting protein 2,
  • DKFZP586G0522,
  • PSORS13,
  • chromosome 6 open reading frame 2,
  • C6orf6,
  • C6orf4,

Description…

From NCBI Gene: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: TRAF3IP2

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

Version 5.0.2